Transcriptional profiling and targeted proteomics reveals common molecular changes associated with cigarette smoke-induced lung emphysema development in five susceptible mouse strains.

Cabanski, Maciej; Fields, Brett; Boue, Stephanie; Boukharov, Natalia; DeLeon, Hector; Dror, Natalie; Geertz, Marcel; Guedj, Emmanuel; Iskandar, Anita; Kogel, Ulrike; Merg, Celine; Peck, Michael J; Poussin, Carine; Schlage, Walter K; Talikka, Marja; Ivanov, Nikolai V; Hoeng, Julia; Peitsch, Manuel C

Cabanski, Maciej; Fields, Brett; Boue, Stephanie; Boukharov, Natalia; DeLeon, Hector; Dror, Natalie; Geertz, Marcel; Guedj, Emmanuel; Iskandar, Anita; Kogel, Ulrike; Merg, Celine; Peck, Michael J; Poussin, Carine; Schlage, Walter K; Talikka, Marja; Ivanov, Nikolai V; Hoeng, Julia; Peitsch, Manuel C.

Affiliation

Cabanski M; Philip Morris International Research and Development, Philip Morris Products S.A, Quai Jeanrenaud 5, 2000, Neuchâtel, Switzerland.

Inflamm Res ; 64(7): 471-86, 2015 Jul.

Article in En | MEDLINE | ID: mdl-25962837

Subject(s)

Nicotiana; Pulmonary Emphysema/genetics; Pulmonary Emphysema/pathology; Smoke; Animals; Apolipoproteins E/genetics; Bronchoalveolar Lavage Fluid/chemistry; Bronchoalveolar Lavage Fluid/cytology; Causality; Gene Expression Profiling; Inhalation Exposure; Lung/pathology; Mice; Mice, Inbred C57BL; Mice, Inbred CFTR; Mice, Knockout; Polymerase Chain Reaction; Proteomics; Pulmonary Emphysema/chemically induced; Smoking; Species Specificity

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pulmonary Emphysema / Smoke / Nicotiana Type of study: Prognostic_studies / Risk_factors_studies Limits: Animals Language: En Journal: Inflamm Res Journal subject: ALERGIA E IMUNOLOGIA / PATOLOGIA Year: 2015 Type: Article Affiliation country: Switzerland

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