Structural Basis for Receptor Activity-Modifying Protein-Dependent Selective Peptide Recognition by a G Protein-Coupled Receptor.

Booe, Jason M; Walker, Christopher S; Barwell, James; Kuteyi, Gabriel; Simms, John; Jamaluddin, Muhammad A; Warner, Margaret L; Bill, Roslyn M; Harris, Paul W; Brimble, Margaret A; Poyner, David R; Hay, Debbie L; Pioszak, Augen A

Booe, Jason M; Walker, Christopher S; Barwell, James; Kuteyi, Gabriel; Simms, John; Jamaluddin, Muhammad A; Warner, Margaret L; Bill, Roslyn M; Harris, Paul W; Brimble, Margaret A; Poyner, David R; Hay, Debbie L; Pioszak, Augen A.

Affiliation

Booe JM; Department of Biochemistry and Molecular Biology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA.
Walker CS; School of Biological Sciences and Maurice Wilkins Centre, University of Auckland, Auckland 1142, New Zealand.
Barwell J; School of Life and Health Sciences, Aston University, Birmingham, B4 7ET, UK.
Kuteyi G; School of Life and Health Sciences, Aston University, Birmingham, B4 7ET, UK.
Simms J; School of Life and Health Sciences, Aston University, Birmingham, B4 7ET, UK.
Jamaluddin MA; School of Biological Sciences and Maurice Wilkins Centre, University of Auckland, Auckland 1142, New Zealand.
Warner ML; Department of Biochemistry and Molecular Biology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA.
Bill RM; School of Life and Health Sciences, Aston University, Birmingham, B4 7ET, UK.
Harris PW; School of Chemical Sciences and Maurice Wilkins Centre, University of Auckland, Auckland 1142, New Zealand.
Brimble MA; School of Chemical Sciences and Maurice Wilkins Centre, University of Auckland, Auckland 1142, New Zealand.
Poyner DR; School of Life and Health Sciences, Aston University, Birmingham, B4 7ET, UK.
Hay DL; School of Biological Sciences and Maurice Wilkins Centre, University of Auckland, Auckland 1142, New Zealand.
Pioszak AA; Department of Biochemistry and Molecular Biology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA. Electronic address: augen-pioszak@ouhsc.edu.

Mol Cell ; 58(6): 1040-52, 2015 Jun 18.

Article in En | MEDLINE | ID: mdl-25982113

Subject(s)

Calcitonin Receptor-Like Protein/chemistry; Peptides/chemistry; Receptor Activity-Modifying Protein 1/chemistry; Receptor Activity-Modifying Protein 2/chemistry; Adrenomedullin/chemistry; Adrenomedullin/genetics; Adrenomedullin/metabolism; Amino Acid Sequence; Animals; Binding Sites/genetics; COS Cells; Calcitonin Gene-Related Peptide/chemistry; Calcitonin Gene-Related Peptide/genetics; Calcitonin Gene-Related Peptide/metabolism; Calcitonin Receptor-Like Protein/genetics; Calcitonin Receptor-Like Protein/metabolism; Chlorocebus aethiops; Crystallography, X-Ray; Humans; Models, Molecular; Molecular Sequence Data; Mutation; Peptides/genetics; Peptides/metabolism; Protein Binding; Protein Multimerization; Protein Structure, Secondary; Protein Structure, Tertiary; Receptor Activity-Modifying Protein 1/genetics; Receptor Activity-Modifying Protein 1/metabolism; Receptor Activity-Modifying Protein 2/genetics; Receptor Activity-Modifying Protein 2/metabolism; Sequence Homology, Amino Acid

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Peptides / Receptor Activity-Modifying Protein 1 / Receptor Activity-Modifying Protein 2 / Calcitonin Receptor-Like Protein Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Mol Cell Journal subject: BIOLOGIA MOLECULAR Year: 2015 Type: Article Affiliation country: United States

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