The Bacterial Sec Pathway of Protein Export: Screening and Follow-Up.

Crowther, Gregory J; Weller, Sara M; Jones, Jackson C; Weaver, Tatiana; Fan, Erkang; Van Voorhis, Wesley C; Rosen, Henry

Crowther, Gregory J; Weller, Sara M; Jones, Jackson C; Weaver, Tatiana; Fan, Erkang; Van Voorhis, Wesley C; Rosen, Henry.

Affiliation

Crowther GJ; Department of Medicine, University of Washington, Seattle, WA, USA crowther@uw.edu.
Weller SM; Department of Medicine, University of Washington, Seattle, WA, USA.
Jones JC; Department of Medicine, University of Washington, Seattle, WA, USA.
Weaver T; Department of Medicine, University of Washington, Seattle, WA, USA.
Fan E; Department of Biochemistry, University of Washington, Seattle, WA, USA.
Van Voorhis WC; Department of Medicine, University of Washington, Seattle, WA, USA.
Rosen H; Department of Medicine, University of Washington, Seattle, WA, USA.

J Biomol Screen ; 20(7): 921-6, 2015 Aug.

Article in En | MEDLINE | ID: mdl-25987586

Subject(s)

Bacterial Proteins/metabolism; Bacterial Secretion Systems; Anti-Bacterial Agents/chemistry; Anti-Bacterial Agents/metabolism; Anti-Bacterial Agents/pharmacology; Bacterial Proteins/genetics; Dose-Response Relationship, Drug; Drug Discovery/methods; Gene Expression/drug effects; High-Throughput Screening Assays; Protein Transport/drug effects; Small Molecule Libraries; beta-Galactosidase/genetics; beta-Galactosidase/metabolism

Key words

SecE; SecG; SecY; drug development; protein translocation; translocase

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Bacterial Proteins / Bacterial Secretion Systems Type of study: Diagnostic_studies / Screening_studies Language: En Journal: J Biomol Screen Journal subject: BIOLOGIA MOLECULAR Year: 2015 Type: Article Affiliation country: United States

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