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Functional loss of IκBε leads to NF-κB deregulation in aggressive chronic lymphocytic leukemia.
Mansouri, Larry; Sutton, Lesley-Ann; Ljungström, Viktor; Bondza, Sina; Arngården, Linda; Bhoi, Sujata; Larsson, Jimmy; Cortese, Diego; Kalushkova, Antonia; Plevova, Karla; Young, Emma; Gunnarsson, Rebeqa; Falk-Sörqvist, Elin; Lönn, Peter; Muggen, Alice F; Yan, Xiao-Jie; Sander, Birgitta; Enblad, Gunilla; Smedby, Karin E; Juliusson, Gunnar; Belessi, Chrysoula; Rung, Johan; Chiorazzi, Nicholas; Strefford, Jonathan C; Langerak, Anton W; Pospisilova, Sarka; Davi, Frederic; Hellström, Mats; Jernberg-Wiklund, Helena; Ghia, Paolo; Söderberg, Ola; Stamatopoulos, Kostas; Nilsson, Mats; Rosenquist, Richard.
Affiliation
  • Mansouri L; Department of Immunology, Genetics, and Pathology, Science for Life Laboratory, Uppsala University, 751 05 Uppsala, Sweden.
  • Sutton LA; Department of Immunology, Genetics, and Pathology, Science for Life Laboratory, Uppsala University, 751 05 Uppsala, Sweden.
  • Ljungström V; Department of Immunology, Genetics, and Pathology, Science for Life Laboratory, Uppsala University, 751 05 Uppsala, Sweden.
  • Bondza S; Department of Immunology, Genetics, and Pathology, Science for Life Laboratory, Uppsala University, 751 05 Uppsala, Sweden.
  • Arngården L; Department of Immunology, Genetics, and Pathology, Science for Life Laboratory, Uppsala University, 751 05 Uppsala, Sweden.
  • Bhoi S; Department of Immunology, Genetics, and Pathology, Science for Life Laboratory, Uppsala University, 751 05 Uppsala, Sweden.
  • Larsson J; Department of Immunology, Genetics, and Pathology, Science for Life Laboratory, Uppsala University, 751 05 Uppsala, Sweden.
  • Cortese D; Department of Immunology, Genetics, and Pathology, Science for Life Laboratory, Uppsala University, 751 05 Uppsala, Sweden.
  • Kalushkova A; Department of Immunology, Genetics, and Pathology, Science for Life Laboratory, Uppsala University, 751 05 Uppsala, Sweden.
  • Plevova K; Central European Institute of Technology, Masaryk University and University Hospital Brno, 601 77 Brno, Czech Republic.
  • Young E; Department of Immunology, Genetics, and Pathology, Science for Life Laboratory, Uppsala University, 751 05 Uppsala, Sweden.
  • Gunnarsson R; Department of Immunology, Genetics, and Pathology, Science for Life Laboratory, Uppsala University, 751 05 Uppsala, Sweden.
  • Falk-Sörqvist E; Department of Immunology, Genetics, and Pathology, Science for Life Laboratory, Uppsala University, 751 05 Uppsala, Sweden.
  • Lönn P; Department of Immunology, Genetics, and Pathology, Science for Life Laboratory, Uppsala University, 751 05 Uppsala, Sweden.
  • Muggen AF; Department of Immunology, Erasmus MC, University Medical Center Rotterdam, 3000 CE Rotterdam, Netherlands.
  • Yan XJ; The Karches Center for Chronic Lymphocytic Leukemia Research, The Feinstein Institute for Medical Research, Manhasset, NY 11030.
  • Sander B; Department of Laboratory Medicine, Division of Pathology, Karolinska Institutet and Karolinska University Hospital, 141 86 Huddinge, Stockholm, Sweden.
  • Enblad G; Department of Immunology, Genetics, and Pathology, Science for Life Laboratory, Uppsala University, 751 05 Uppsala, Sweden.
  • Smedby KE; Clinical Epidemiology Unit, Department of Medicine, Karolinska Institutet, 171 76 Stockholm, Sweden.
  • Juliusson G; Department of Laboratory Medicine, Lund Stem Cell Center, Lund University, 22184 Lund, Sweden.
  • Belessi C; Hematology Department, General Hospital of Nikea, 18454 Piraeus, Greece.
  • Rung J; Department of Immunology, Genetics, and Pathology, Science for Life Laboratory, Uppsala University, 751 05 Uppsala, Sweden.
  • Chiorazzi N; The Karches Center for Chronic Lymphocytic Leukemia Research, The Feinstein Institute for Medical Research, Manhasset, NY 11030.
  • Strefford JC; Cancer Sciences Academic Unit, Faculty of Medicine, University of Southampton, Southampton SO16 6YD, England, UK.
  • Langerak AW; Department of Immunology, Erasmus MC, University Medical Center Rotterdam, 3000 CE Rotterdam, Netherlands.
  • Pospisilova S; Central European Institute of Technology, Masaryk University and University Hospital Brno, 601 77 Brno, Czech Republic.
  • Davi F; Department of Hematology, Pitié-Salpêtrière Hospital, F-75013 Paris, France Cordeliers Research Center, UMR_S 1138, UPMC University of Paris 6, F-75005 Paris, France.
  • Hellström M; Department of Immunology, Genetics, and Pathology, Science for Life Laboratory, Uppsala University, 751 05 Uppsala, Sweden.
  • Jernberg-Wiklund H; Department of Immunology, Genetics, and Pathology, Science for Life Laboratory, Uppsala University, 751 05 Uppsala, Sweden.
  • Ghia P; Divisione di Oncologia Sperimentale, Dipartimento di Onco-Ematologia, IRCCS Istituto Scientifico San Raffaele and Fondazione Centro San Raffaele, 20132 Milano, Italy Università Vita-Salute San Raffaele, 20132 Milano, Italy.
  • Söderberg O; Department of Immunology, Genetics, and Pathology, Science for Life Laboratory, Uppsala University, 751 05 Uppsala, Sweden.
  • Stamatopoulos K; Department of Immunology, Genetics, and Pathology, Science for Life Laboratory, Uppsala University, 751 05 Uppsala, Sweden Institute of Applied Biosciences, Center for Research and Technology Hellas, 57001 Thessaloniki, Greece.
  • Nilsson M; Department of Immunology, Genetics, and Pathology, Science for Life Laboratory, Uppsala University, 751 05 Uppsala, Sweden Department of Biochemistry and Biophysics, Science for Life Laboratory, Stockholm University, 106 91 Stockholm, Sweden.
  • Rosenquist R; Department of Immunology, Genetics, and Pathology, Science for Life Laboratory, Uppsala University, 751 05 Uppsala, Sweden richard.rosenquist@igp.uu.se.
J Exp Med ; 212(6): 833-43, 2015 Jun 01.
Article in En | MEDLINE | ID: mdl-25987724
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Leukemia, Lymphocytic, Chronic, B-Cell / Gene Expression Regulation, Leukemic / NF-kappa B / I-kappa B Kinase Type of study: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Humans Language: En Journal: J Exp Med Year: 2015 Type: Article Affiliation country: Sweden
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Leukemia, Lymphocytic, Chronic, B-Cell / Gene Expression Regulation, Leukemic / NF-kappa B / I-kappa B Kinase Type of study: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Humans Language: En Journal: J Exp Med Year: 2015 Type: Article Affiliation country: Sweden