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Metabolism and Disposition of Cabozantinib in Healthy Male Volunteers and Pharmacologic Characterization of Its Major Metabolites.
Lacy, Steven; Hsu, Bih; Miles, Dale; Aftab, Dana; Wang, Ronghua; Nguyen, Linh.
Affiliation
  • Lacy S; Department of Non-Clinical Development (S.L., B.H., D.M., L.N.) and Translational Medicine (D.A.), Exelixis, Inc., South San Francisco, California; and QPS, LLC, Newark, Delaware (R.W.) slacy@exelixis.com.
  • Hsu B; Department of Non-Clinical Development (S.L., B.H., D.M., L.N.) and Translational Medicine (D.A.), Exelixis, Inc., South San Francisco, California; and QPS, LLC, Newark, Delaware (R.W.).
  • Miles D; Department of Non-Clinical Development (S.L., B.H., D.M., L.N.) and Translational Medicine (D.A.), Exelixis, Inc., South San Francisco, California; and QPS, LLC, Newark, Delaware (R.W.).
  • Aftab D; Department of Non-Clinical Development (S.L., B.H., D.M., L.N.) and Translational Medicine (D.A.), Exelixis, Inc., South San Francisco, California; and QPS, LLC, Newark, Delaware (R.W.).
  • Wang R; Department of Non-Clinical Development (S.L., B.H., D.M., L.N.) and Translational Medicine (D.A.), Exelixis, Inc., South San Francisco, California; and QPS, LLC, Newark, Delaware (R.W.).
  • Nguyen L; Department of Non-Clinical Development (S.L., B.H., D.M., L.N.) and Translational Medicine (D.A.), Exelixis, Inc., South San Francisco, California; and QPS, LLC, Newark, Delaware (R.W.).
Drug Metab Dispos ; 43(8): 1190-207, 2015 Aug.
Article in En | MEDLINE | ID: mdl-26015560
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyridines / Protein Kinase Inhibitors / Anilides Type of study: Prognostic_studies Limits: Adult / Animals / Humans / Male / Middle aged Language: En Journal: Drug Metab Dispos Journal subject: FARMACOLOGIA Year: 2015 Type: Article
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyridines / Protein Kinase Inhibitors / Anilides Type of study: Prognostic_studies Limits: Adult / Animals / Humans / Male / Middle aged Language: En Journal: Drug Metab Dispos Journal subject: FARMACOLOGIA Year: 2015 Type: Article