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Activation of the kynurenine pathway and increased production of the excitotoxin quinolinic acid following traumatic brain injury in humans.
Yan, Edwin B; Frugier, Tony; Lim, Chai K; Heng, Benjamin; Sundaram, Gayathri; Tan, May; Rosenfeld, Jeffrey V; Walker, David W; Guillemin, Gilles J; Morganti-Kossmann, Maria Cristina.
Affiliation
  • Yan EB; Department of Physiology, Monash University, Clayton, VIC, 3800, Australia. edwin.yan@monash.edu.
  • Frugier T; Department of Pharmacology and Therapeutics, The University of Melbourne, Melbourne, Australia.
  • Lim CK; Neuroinflammation group, Faculty of Medicine and Health Sciences, Macquarie University, Sydney, Australia.
  • Heng B; Neuroinflammation group, Faculty of Medicine and Health Sciences, Macquarie University, Sydney, Australia.
  • Sundaram G; Applied Neurosciences Program, Peter Duncan Neurosciences Research Unit, St Vincent's Centre for Applied Medical Research, Sydney, Australia.
  • Tan M; Hospital Queen Elizabeth, Karung Berkunci No. 2029, 88586, Kota Kinabalu, Sabah, Malaysia.
  • Rosenfeld JV; Department of Neurosurgery, The Alfred Hospital, Melbourne, Australia.
  • Walker DW; Department of Surgery, Central Clinical School and Monash Institute of Medical Engineering, Monash University, Melbourne, Australia.
  • Guillemin GJ; The Ritchie Centre, Hudson Institute of Medical Research, Monash Medical Centre, Melbourne, Australia.
  • Morganti-Kossmann MC; Neuroinflammation group, Faculty of Medicine and Health Sciences, Macquarie University, Sydney, Australia.
J Neuroinflammation ; 12: 110, 2015 May 30.
Article in En | MEDLINE | ID: mdl-26025142
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Brain Injuries / Signal Transduction / Quinolinic Acid / Kynurenine / Neurotoxins Type of study: Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged Language: En Journal: J Neuroinflammation Journal subject: NEUROLOGIA Year: 2015 Type: Article Affiliation country: Australia
Fulltext
Print
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Brain Injuries / Signal Transduction / Quinolinic Acid / Kynurenine / Neurotoxins Type of study: Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged Language: En Journal: J Neuroinflammation Journal subject: NEUROLOGIA Year: 2015 Type: Article Affiliation country: Australia