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Kinase-Independent Small-Molecule Inhibition of JAK-STAT Signaling.
Chou, Danny Hung-Chieh; Vetere, Amedeo; Choudhary, Amit; Scully, Stephen S; Schenone, Monica; Tang, Alicia; Gomez, Rachel; Burns, Sean M; Lundh, Morten; Vital, Tamara; Comer, Eamon; Faloon, Patrick W; Dancík, Vlado; Ciarlo, Christie; Paulk, Joshiawa; Dai, Mingji; Reddy, Clark; Sun, Hanshi; Young, Matthew; Donato, Nicholas; Jaffe, Jacob; Clemons, Paul A; Palmer, Michelle; Carr, Steven A; Schreiber, Stuart L; Wagner, Bridget K.
Affiliation
  • Chou DH; ‡Department of Chemistry and Chemical Biology, Harvard University, 12 Oxford Street, Cambridge, Massachusetts 02138, United States.
  • Choudhary A; §Society of Fellows, Harvard University, 78 Mount Auburn Street, Cambridge, Massachusetts 02138, United States.
  • Sun H; #Department of Internal Medicine, University of Michigan Comprehensive Cancer Center, 1500 E. Medical Center Drive, Ann Arbor, Michigan 48103, United States.
  • Young M; ∇Department of Pharmacology, University of Michigan Medical School, 1150 W. Medical Center Drive, Ann Arbor, Michigan 48109, United States.
  • Donato N; #Department of Internal Medicine, University of Michigan Comprehensive Cancer Center, 1500 E. Medical Center Drive, Ann Arbor, Michigan 48103, United States.
  • Schreiber SL; ‡Department of Chemistry and Chemical Biology, Harvard University, 12 Oxford Street, Cambridge, Massachusetts 02138, United States.
J Am Chem Soc ; 137(24): 7929-34, 2015 Jun 24.
Article in En | MEDLINE | ID: mdl-26042473
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Interferon-gamma / Protective Agents / Insulin-Secreting Cells / STAT1 Transcription Factor / Janus Kinase 2 Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: J Am Chem Soc Year: 2015 Type: Article Affiliation country: United States
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Interferon-gamma / Protective Agents / Insulin-Secreting Cells / STAT1 Transcription Factor / Janus Kinase 2 Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: J Am Chem Soc Year: 2015 Type: Article Affiliation country: United States