Pharmacokinetic and pharmacodynamic interaction of siponimod (BAF312) and propranolol in healthy subjects.

Biswal, Shibadas; Polus, Florine; Pal, Parsar; Veldandi, Uday Kiran; Marbury, Thomas C; Perry, Robert; Legangneux, Eric

Biswal, Shibadas; Polus, Florine; Pal, Parsar; Veldandi, Uday Kiran; Marbury, Thomas C; Perry, Robert; Legangneux, Eric.

Int J Clin Pharmacol Ther ; 53(10): 855-65, 2015 Oct.

Article in En | MEDLINE | ID: mdl-26308174

Subject(s)

Azetidines/pharmacology; Benzyl Compounds/pharmacology; Propranolol/pharmacology; Adult; Azetidines/pharmacokinetics; Benzyl Compounds/pharmacokinetics; Blood Pressure/drug effects; Double-Blind Method; Drug Interactions; Female; Forced Expiratory Volume/drug effects; Heart Rate/drug effects; Humans; Male; Middle Aged; Propranolol/pharmacokinetics; Young Adult

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Propranolol / Azetidines / Benzyl Compounds Type of study: Clinical_trials Limits: Adult / Female / Humans / Male / Middle aged Language: En Journal: Int J Clin Pharmacol Ther Journal subject: FARMACOLOGIA / TERAPIA POR MEDICAMENTOS Year: 2015 Type: Article

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