Cabozantinib for the treatment of non-small cell lung cancer with KIF5B-RET fusion. An example of swift repositioning.

Song, Minsoo; Kim, Seong-Heon; Yoon, Suk Kyoon

Song, Minsoo; Kim, Seong-Heon; Yoon, Suk Kyoon.

Affiliation

Song M; New Drug Development Center (NDDC), Daegu-Gyeongbuk Medical Innovation Foundation (DGMIF), 80 Cheombok-ro, Dong-gu, Daegu, 701-310, Korea. msong@dgmif.re.kr.
Kim SH; New Drug Development Center (NDDC), Daegu-Gyeongbuk Medical Innovation Foundation (DGMIF), 80 Cheombok-ro, Dong-gu, Daegu, 701-310, Korea. seongheonk@dgmif.re.kr.
Yoon SK; New Drug Development Center (NDDC), Daegu-Gyeongbuk Medical Innovation Foundation (DGMIF), 80 Cheombok-ro, Dong-gu, Daegu, 701-310, Korea. skyoon@dgmif.re.kr.

Arch Pharm Res ; 38(12): 2120-3, 2015 Dec.

Article in En | MEDLINE | ID: mdl-26377589

Subject(s)

Adenocarcinoma/metabolism; Anilides/therapeutic use; Carcinoma, Non-Small-Cell Lung/metabolism; Kinesins/metabolism; Lung Neoplasms/metabolism; Proto-Oncogene Proteins c-ret/metabolism; Pyridines/therapeutic use; Adenocarcinoma/drug therapy; Adenocarcinoma of Lung; Anilides/chemistry; Carcinoma, Non-Small-Cell Lung/drug therapy; Clinical Trials as Topic/methods; Humans; Lung Neoplasms/drug therapy; Pyridines/chemistry; Treatment Outcome

Key words

Adenocarcinoma; Cabozantinib; KIF5B-RET; Lung cancer; Non-small cell lung cancer; Small-molecule tyrosine kinase inhibitor

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyridines / Adenocarcinoma / Kinesins / Carcinoma, Non-Small-Cell Lung / Proto-Oncogene Proteins c-ret / Anilides / Lung Neoplasms Limits: Humans Language: En Journal: Arch Pharm Res Year: 2015 Type: Article

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