Energy balance and metabolic changes with sodium-glucose co-transporter 2 inhibition.

Rajeev, S P; Cuthbertson, D J; Wilding, J P H

Rajeev, S P; Cuthbertson, D J; Wilding, J P H.

Affiliation

Rajeev SP; Obesity and Endocrinology Research Group, Institute of Ageing and Chronic Disease, University of Liverpool, Liverpool, UK.
Cuthbertson DJ; Aintree University Hospital NHS Foundation Trust, Liverpool, UK.
Wilding JP; Obesity and Endocrinology Research Group, Institute of Ageing and Chronic Disease, University of Liverpool, Liverpool, UK.

Diabetes Obes Metab ; 18(2): 125-34, 2016 Feb.

Article in En | MEDLINE | ID: mdl-26403227

Subject(s)

Diabetes Mellitus, Type 2/drug therapy; Energy Intake/drug effects; Energy Metabolism/drug effects; Hypoglycemic Agents/therapeutic use; Kidney/drug effects; Membrane Transport Modulators/therapeutic use; Molecular Targeted Therapy; Sodium-Glucose Transporter 2 Inhibitors; Adiposity/drug effects; Animals; Anti-Obesity Agents/adverse effects; Anti-Obesity Agents/therapeutic use; Blood Glucose/metabolism; Diabetes Mellitus, Type 1/complications; Diabetes Mellitus, Type 1/drug therapy; Diabetes Mellitus, Type 1/metabolism; Diabetes Mellitus, Type 2/complications; Diabetes Mellitus, Type 2/metabolism; Diabetic Ketoacidosis/chemically induced; Diabetic Ketoacidosis/prevention & control; Humans; Hypoglycemic Agents/adverse effects; Intestinal Mucosa/drug effects; Intestinal Mucosa/metabolism; Kidney/metabolism; Membrane Transport Modulators/adverse effects; Molecular Targeted Therapy/adverse effects; Obesity/complications; Obesity/drug therapy; Obesity/metabolism; Pancreas/drug effects; Pancreas/metabolism; Renal Elimination/drug effects; Sodium-Glucose Transporter 2/metabolism; Weight Loss/drug effects

Key words

SGLT2 inhibitor; antidiabetic drug; drug mechanism; energy regulation; glucose metabolism; type 2 diabetes

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Energy Intake / Diabetes Mellitus, Type 2 / Energy Metabolism / Membrane Transport Modulators / Molecular Targeted Therapy / Sodium-Glucose Transporter 2 Inhibitors / Hypoglycemic Agents / Kidney Limits: Animals / Humans Language: En Journal: Diabetes Obes Metab Journal subject: ENDOCRINOLOGIA / METABOLISMO Year: 2016 Type: Article Affiliation country: United kingdom

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