Crystal Structure of the Zorbamycin-Binding Protein ZbmA, the Primary Self-Resistance Element in Streptomyces flavoviridis ATCC21892.

Rudolf, Jeffrey D; Bigelow, Lance; Chang, Changsoo; Cuff, Marianne E; Lohman, Jeremy R; Chang, Chin-Yuan; Ma, Ming; Yang, Dong; Clancy, Shonda; Babnigg, Gyorgy; Joachimiak, Andrzej; Phillips, George N; Shen, Ben

Rudolf, Jeffrey D; Bigelow, Lance; Chang, Changsoo; Cuff, Marianne E; Lohman, Jeremy R; Chang, Chin-Yuan; Ma, Ming; Yang, Dong; Clancy, Shonda; Babnigg, Gyorgy; Joachimiak, Andrzej; Phillips, George N; Shen, Ben.

Affiliation

Rudolf JD; Department of Chemistry, The Scripps Research Institute , Jupiter, Florida 33458, United States.
Bigelow L; Midwest Center for Structural Genomics and Structural Biology Center, Biosciences Division, Argonne National Laboratory , Argonne, Illinois 60439, United States.
Chang C; Midwest Center for Structural Genomics and Structural Biology Center, Biosciences Division, Argonne National Laboratory , Argonne, Illinois 60439, United States.
Cuff ME; Midwest Center for Structural Genomics and Structural Biology Center, Biosciences Division, Argonne National Laboratory , Argonne, Illinois 60439, United States.
Lohman JR; Department of Chemistry, The Scripps Research Institute , Jupiter, Florida 33458, United States.
Chang CY; Department of Chemistry, The Scripps Research Institute , Jupiter, Florida 33458, United States.
Ma M; Department of Chemistry, The Scripps Research Institute , Jupiter, Florida 33458, United States.
Yang D; Department of Chemistry, The Scripps Research Institute , Jupiter, Florida 33458, United States.
Clancy S; Midwest Center for Structural Genomics and Structural Biology Center, Biosciences Division, Argonne National Laboratory , Argonne, Illinois 60439, United States.
Babnigg G; Midwest Center for Structural Genomics and Structural Biology Center, Biosciences Division, Argonne National Laboratory , Argonne, Illinois 60439, United States.
Joachimiak A; Midwest Center for Structural Genomics and Structural Biology Center, Biosciences Division, Argonne National Laboratory , Argonne, Illinois 60439, United States.
Phillips GN; BioSciences at Rice and Department of Chemistry, Rice University , Houston, Texas 77251, United States.
Shen B; Department of Chemistry, The Scripps Research Institute , Jupiter, Florida 33458, United States.

Biochemistry ; 54(45): 6842-51, 2015 Nov 17.

Article in En | MEDLINE | ID: mdl-26512730

Subject(s)

Antibiotics, Antineoplastic/chemistry; Bacterial Proteins/chemistry; Carrier Proteins/chemistry; Drug Resistance, Microbial/physiology; Streptomyces/chemistry; Amino Acid Sequence; Bacterial Proteins/genetics; Bacterial Proteins/metabolism; Binding Sites; Carbohydrate Conformation; Carrier Proteins/genetics; Carrier Proteins/metabolism; Conserved Sequence; Crystallization; Crystallography, X-Ray; Drug Resistance, Microbial/genetics; Genes, Bacterial; Glycopeptides/metabolism; Glycopeptides/pharmacology; Ligands; Models, Molecular; Molecular Sequence Data; Molecular Structure; Protein Conformation; Sequence Alignment; Sequence Homology, Amino Acid; Streptomyces/genetics; Structure-Activity Relationship

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Streptomyces / Bacterial Proteins / Drug Resistance, Microbial / Carrier Proteins / Antibiotics, Antineoplastic Language: En Journal: Biochemistry Year: 2015 Type: Article Affiliation country: United States

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