The Keap1/Nrf2 pathway in health and disease: from the bench to the clinic.

O'Connell, Maria A; Hayes, John D

O'Connell, Maria A; Hayes, John D.

Affiliation

O'Connell MA; School of Pharmacy, University of East Anglia, Norwich Research Park, Norwich, NR4 7TJ, U.K. m.oconnell@uea.ac.uk.
Hayes JD; Jacqui Wood Cancer Centre, Division of Cancer Research, Medical Research Institute, Ninewells Hospital and Medical School, University of Dundee, Dundee DD1 9SY, U.K.

Biochem Soc Trans ; 43(4): 687-9, 2015 Aug.

Article in En | MEDLINE | ID: mdl-26551713

Subject(s)

Intracellular Signaling Peptides and Proteins/metabolism; NF-E2-Related Factor 2/metabolism; Animals; Congresses as Topic; Homeostasis; Humans; Kelch-Like ECH-Associated Protein 1; Oxidation-Reduction; Signal Transduction

Key words

Kelch-like ECH-associated protein-1 (Keap1); cytoprotection; nuclear factor-erythroid 2 p45-related factor 2 (Nrf2); redox; signalling; stress

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Intracellular Signaling Peptides and Proteins / NF-E2-Related Factor 2 Limits: Animals / Humans Language: En Journal: Biochem Soc Trans Year: 2015 Type: Article Affiliation country: United kingdom

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