Synthesis of di- and tri-saccharide fragments of Salmonella typhi Vi capsular polysaccharide and their zwitterionic analogues.

Fusari, Matteo; Fallarini, Silvia; Lombardi, Grazia; Lay, Luigi

Fusari, Matteo; Fallarini, Silvia; Lombardi, Grazia; Lay, Luigi.

Affiliation

Fusari M; Department of Chemistry and CRC Materiali Polimerici (LaMPo), University of Milan, Via Golgi 19, 20133 Milan, Italy.
Fallarini S; Department of Pharmaceutical Sciences, University of 'Piemonte Orientale, A. Avogadro', Largo Donegani 2, Novara, Italy.
Lombardi G; Department of Pharmaceutical Sciences, University of 'Piemonte Orientale, A. Avogadro', Largo Donegani 2, Novara, Italy.
Lay L; Department of Chemistry and CRC Materiali Polimerici (LaMPo), University of Milan, Via Golgi 19, 20133 Milan, Italy. Electronic address: luigi.lay@unimi.it.

Bioorg Med Chem ; 23(23): 7439-47, 2015 Dec 01.

Article in En | MEDLINE | ID: mdl-26558515

Subject(s)

Amino Sugars/chemical synthesis; Disaccharides/chemical synthesis; Polysaccharides, Bacterial/chemistry; Trisaccharides/chemical synthesis; Amino Sugars/chemistry; Amino Sugars/immunology; Animals; Antibodies/immunology; Disaccharides/chemistry; Disaccharides/immunology; Enzyme-Linked Immunosorbent Assay; Horses; Polysaccharides, Bacterial/immunology; Salmonella typhi; Structure-Activity Relationship; Trisaccharides/chemistry; Trisaccharides/immunology

Key words

Glycoconjugate vaccines; Glycosylation; Salmonella typhi; Vi antigen; Zwitterionic polysaccharides

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Polysaccharides, Bacterial / Trisaccharides / Disaccharides / Amino Sugars Limits: Animals Language: En Journal: Bioorg Med Chem Journal subject: BIOQUIMICA / QUIMICA Year: 2015 Type: Article Affiliation country: Italy

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