Effects of 2-Octynyladenosine (YT-146) on Mitochondrial Function in Ischemic/Reperfused Rat Hearts.

Sasamori, Jun; Abe, Yohei; Marunouchi, Tetsuro; Manome, Yoichi; Uchibori, Takehiro; Tanonaka, Kouichi

Sasamori, Jun; Abe, Yohei; Marunouchi, Tetsuro; Manome, Yoichi; Uchibori, Takehiro; Tanonaka, Kouichi.

Affiliation

Sasamori J; Drug Research Department, Fukushima Research Laboratories, Toa Eiyo Ltd.

Biol Pharm Bull ; 38(12): 1946-53, 2015.

Article in En | MEDLINE | ID: mdl-26632185

Subject(s)

Adenosine/analogs & derivatives; Alkynes/pharmacology; Heart/drug effects; Mitochondria, Heart/drug effects; Myocardial Contraction/drug effects; Myocardial Ischemia/physiopathology; Myocardial Reperfusion Injury/physiopathology; Myocardium; Adenosine/pharmacology; Adenosine/therapeutic use; Adenosine Triphosphate/metabolism; Alkynes/therapeutic use; Animals; Cardiovascular Agents/pharmacology; Cardiovascular Agents/therapeutic use; Energy Metabolism/drug effects; Heart/physiopathology; Male; Mitochondria, Heart/metabolism; Mitochondria, Heart/physiology; Myocardial Contraction/physiology; Myocardial Ischemia/drug therapy; Myocardial Ischemia/metabolism; Myocardial Reperfusion Injury/metabolism; Myocardial Reperfusion Injury/prevention & control; Myocardium/metabolism; Myocardium/pathology; Purinergic P1 Receptor Agonists/pharmacology; Purinergic P1 Receptor Agonists/therapeutic use; Rats, Wistar; Sodium/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Myocardial Reperfusion Injury / Adenosine / Myocardial Ischemia / Alkynes / Heart / Mitochondria, Heart / Myocardial Contraction / Myocardium Limits: Animals Language: En Journal: Biol Pharm Bull Journal subject: BIOQUIMICA / FARMACOLOGIA Year: 2015 Type: Article

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