Escitalopram reversed the traumatic stress-induced depressed and anxiety-like symptoms but not the deficits of fear memory.

Lin, Chen-Cheng; Tung, Che-Se; Liu, Yia-Ping

Lin, Chen-Cheng; Tung, Che-Se; Liu, Yia-Ping.

Affiliation

Lin CC; Department of Physiology and Biophysics, National Defense Medical Center, Taipei, 11490, Taiwan.
Tung CS; Division of Medical Research and Education, Cheng Hsin General Hospital, Taipei, 11220, Taiwan.
Liu YP; Department of Physiology and Biophysics, National Defense Medical Center, Taipei, 11490, Taiwan. yiaping@ms75.hinet.net.

Psychopharmacology (Berl) ; 233(7): 1135-46, 2016 Apr.

Article in En | MEDLINE | ID: mdl-26740318

Subject(s)

Anxiety/drug therapy; Citalopram/therapeutic use; Depression/drug therapy; Fear/drug effects; Memory/drug effects; Selective Serotonin Reuptake Inhibitors/pharmacology; Stress Disorders, Post-Traumatic/drug therapy; Animals; Anxiety/metabolism; Brain/drug effects; Brain/metabolism; Citalopram/pharmacology; Depression/metabolism; Disease Models, Animal; Rats; Rats, Wistar; Serotonin/metabolism; Selective Serotonin Reuptake Inhibitors/therapeutic use; Stress Disorders, Post-Traumatic/metabolism

Key words

Anxiety; Depression; Fear memory; Posttraumatic stress disorder; Selective serotonin reuptake inhibitor; Serotonin

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Anxiety / Stress Disorders, Post-Traumatic / Citalopram / Selective Serotonin Reuptake Inhibitors / Depression / Fear / Memory Type of study: Diagnostic_studies / Guideline Limits: Animals Language: En Journal: Psychopharmacology (Berl) Year: 2016 Type: Article Affiliation country: Taiwan

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