Pax8 plays a pivotal role in regulation of cardiomyocyte growth and senescence.

Wu, Yihao; Zhou, Xi; Huang, Xiaoyan; Xia, Quan; Chen, Zhe; Zhang, Xingwei; Yang, Deye; Geng, Yong-jian

Wu, Yihao; Zhou, Xi; Huang, Xiaoyan; Xia, Quan; Chen, Zhe; Zhang, Xingwei; Yang, Deye; Geng, Yong-jian.

Affiliation

Wu Y; Division of Cardiology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.
Zhou X; Division of Cardiology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.
Huang X; Division of Cardiology, The Affiliated Hospital of Hangzhou Normal University, Hangzhou, China.
Xia Q; Division of Cardiology, The Affiliated Hospital of Hangzhou Normal University, Hangzhou, China.
Chen Z; Division of Cardiology, The Affiliated Hospital of Hangzhou Normal University, Hangzhou, China.
Zhang X; Division of Cardiology, The Affiliated Hospital of Hangzhou Normal University, Hangzhou, China.
Yang D; Division of Cardiology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.
Geng YJ; Division of Cardiology, The Affiliated Hospital of Hangzhou Normal University, Hangzhou, China.

J Cell Mol Med ; 20(4): 644-54, 2016 Apr.

Article in En | MEDLINE | ID: mdl-26781745

Subject(s)

Bone Morphogenetic Protein Receptors, Type I/genetics; Heart Septal Defects, Ventricular/genetics; Myocardium/metabolism; Myocytes, Cardiac/metabolism; PAX8 Transcription Factor/genetics; Animals; Animals, Newborn; Apoptosis/genetics; Bone Morphogenetic Protein Receptors, Type I/antagonists & inhibitors; Bone Morphogenetic Protein Receptors, Type I/metabolism; Cell Line; Cellular Senescence; Gene Expression Regulation, Developmental; Heart Septal Defects, Ventricular/metabolism; Heart Septal Defects, Ventricular/pathology; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle Development/genetics; Myocardium/pathology; Myocytes, Cardiac/pathology; PAX8 Transcription Factor/deficiency; Primary Cell Culture; RNA, Small Interfering/genetics; RNA, Small Interfering/metabolism; Signal Transduction

Key words

ALK3; Pax8; apoptosis; senescence; ventricular septal defect

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Myocytes, Cardiac / Bone Morphogenetic Protein Receptors, Type I / PAX8 Transcription Factor / Heart Septal Defects, Ventricular / Myocardium Limits: Animals Language: En Journal: J Cell Mol Med Journal subject: BIOLOGIA MOLECULAR Year: 2016 Type: Article Affiliation country: China

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