Hedgehog receptor function during craniofacial development.

Xavier, Guilherme M; Seppala, Maisa; Barrell, William; Birjandi, Anahid A; Geoghegan, Finn; Cobourne, Martyn T

Xavier, Guilherme M; Seppala, Maisa; Barrell, William; Birjandi, Anahid A; Geoghegan, Finn; Cobourne, Martyn T.

Affiliation

Xavier GM; Department of Craniofacial Development and Stem Cell Biology, King's College London Dental Institute, Floor 27, Guy's Hospital, London SE1 9RT, UK; Department of Orthodontics, King's College London Dental Institute, Floor 27, Guy's Hospital, London SE1 9RT, UK.
Seppala M; Department of Craniofacial Development and Stem Cell Biology, King's College London Dental Institute, Floor 27, Guy's Hospital, London SE1 9RT, UK; Department of Orthodontics, King's College London Dental Institute, Floor 27, Guy's Hospital, London SE1 9RT, UK.
Barrell W; Department of Craniofacial Development and Stem Cell Biology, King's College London Dental Institute, Floor 27, Guy's Hospital, London SE1 9RT, UK.
Birjandi AA; Department of Craniofacial Development and Stem Cell Biology, King's College London Dental Institute, Floor 27, Guy's Hospital, London SE1 9RT, UK.
Geoghegan F; Department of Craniofacial Development and Stem Cell Biology, King's College London Dental Institute, Floor 27, Guy's Hospital, London SE1 9RT, UK.
Cobourne MT; Department of Craniofacial Development and Stem Cell Biology, King's College London Dental Institute, Floor 27, Guy's Hospital, London SE1 9RT, UK; Department of Orthodontics, King's College London Dental Institute, Floor 27, Guy's Hospital, London SE1 9RT, UK. Electronic address: martyn.cobourne@kc

Dev Biol ; 415(2): 198-215, 2016 07 15.

Article in En | MEDLINE | ID: mdl-26875496

Subject(s)

Craniofacial Abnormalities/embryology; Hedgehog Proteins/physiology; Maxillofacial Development/physiology; Patched Receptors/physiology; Signal Transduction; Animals; Cell Movement; Cilia/physiology; Ciliopathies/embryology; Ciliopathies/genetics; Ciliopathies/physiopathology; Craniofacial Abnormalities/genetics; Craniofacial Abnormalities/physiopathology; Diencephalon/embryology; Disease Models, Animal; Ectoderm/embryology; Endoderm/embryology; Face/abnormalities; Face/embryology; Gene Expression Regulation, Developmental; Holoprosencephaly/embryology; Holoprosencephaly/genetics; Holoprosencephaly/physiopathology; Humans; Maxillofacial Development/genetics; Membrane Proteins/physiology; Neural Crest/cytology; Neural Crest/embryology; Patched Receptors/genetics; Signal Transduction/genetics; Skull/abnormalities; Skull/embryology

Key words

Boc; Cdon; Craniofacial development; Disease; Dispatched; EvC1/2; Gas1; Gpr161; Holoprosencephaly; Lrp2/megalin; Patched1; Patched2; Scube2; Smoothened; Sonic hedgehog

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Signal Transduction / Craniofacial Abnormalities / Hedgehog Proteins / Patched Receptors / Maxillofacial Development Limits: Animals / Humans Language: En Journal: Dev Biol Year: 2016 Type: Article Affiliation country: United kingdom

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