Enzymatic reduction of acetophenone derivatives with a benzil reductase from Pichia glucozyma (KRED1-Pglu): electronic and steric effects on activity and enantioselectivity.

Contente, Martina L; Serra, Immacolata; Palazzolo, Luca; Parravicini, Chiara; Gianazza, Elisabetta; Eberini, Ivano; Pinto, Andrea; Guidi, Benedetta; Molinari, Francesco; Romano, Diego

Contente, Martina L; Serra, Immacolata; Palazzolo, Luca; Parravicini, Chiara; Gianazza, Elisabetta; Eberini, Ivano; Pinto, Andrea; Guidi, Benedetta; Molinari, Francesco; Romano, Diego.

Affiliation

Contente ML; Department of Food, Nutritional and Environmental Sciences (DeFENS), University of Milan, Via Mangiagalli 25, 20133 Milano, Italy. diego.romano@unimi.it.

Org Biomol Chem ; 14(13): 3404-8, 2016 Apr 07.

Article in En | MEDLINE | ID: mdl-26952764

Subject(s)

Acetophenones/metabolism; Alcohol Oxidoreductases/metabolism; Pichia/enzymology; Acetophenones/chemistry; Alcohol Oxidoreductases/chemistry; Electrons; Molecular Structure; Oxidation-Reduction; Stereoisomerism; Substrate Specificity

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Acetophenones / Pichia / Alcohol Oxidoreductases Language: En Journal: Org Biomol Chem Journal subject: BIOQUIMICA / QUIMICA Year: 2016 Type: Article Affiliation country: Italy

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