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T-cell activation is an immune correlate of risk in BCG vaccinated infants.
Fletcher, Helen A; Snowden, Margaret A; Landry, Bernard; Rida, Wasima; Satti, Iman; Harris, Stephanie A; Matsumiya, Magali; Tanner, Rachel; O'Shea, Matthew K; Dheenadhayalan, Veerabadran; Bogardus, Leah; Stockdale, Lisa; Marsay, Leanne; Chomka, Agnieszka; Harrington-Kandt, Rachel; Manjaly-Thomas, Zita-Rose; Naranbhai, Vivek; Stylianou, Elena; Darboe, Fatoumatta; Penn-Nicholson, Adam; Nemes, Elisa; Hatherill, Mark; Hussey, Gregory; Mahomed, Hassan; Tameris, Michele; McClain, J Bruce; Evans, Thomas G; Hanekom, Willem A; Scriba, Thomas J; McShane, Helen.
Affiliation
  • Fletcher HA; Jenner Institute, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7DQ, UK.
  • Snowden MA; Department of Immunology and Infection, London School of Hygiene and Tropical Medicine, London W1CE7HT, UK.
  • Landry B; Aeras, Rockville, Maryland 20850, USA.
  • Rida W; Aeras, Rockville, Maryland 20850, USA.
  • Satti I; Biostatistics Consultant, 1129 N. Illinois Street, Arlington, Virginia 22205, USA.
  • Harris SA; Jenner Institute, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7DQ, UK.
  • Matsumiya M; Jenner Institute, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7DQ, UK.
  • Tanner R; Jenner Institute, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7DQ, UK.
  • O'Shea MK; Jenner Institute, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7DQ, UK.
  • Dheenadhayalan V; Jenner Institute, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7DQ, UK.
  • Bogardus L; Aeras, Rockville, Maryland 20850, USA.
  • Stockdale L; Aeras, Rockville, Maryland 20850, USA.
  • Marsay L; Jenner Institute, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7DQ, UK.
  • Chomka A; Department of Immunology and Infection, London School of Hygiene and Tropical Medicine, London W1CE7HT, UK.
  • Harrington-Kandt R; Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford OX3 7LE, UK.
  • Manjaly-Thomas ZR; Kennedy Institute, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford OX3 7LF, UK.
  • Naranbhai V; Jenner Institute, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7DQ, UK.
  • Stylianou E; Jenner Institute, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7DQ, UK.
  • Darboe F; Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford OX37BN, UK.
  • Penn-Nicholson A; Jenner Institute, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7DQ, UK.
  • Nemes E; South African Tuberculosis Vaccine Initiative, Institute of Infectious Disease and Molecular Medicine, Department of Paediatrics and Child Health, University of Cape Town, Cape Town 7935, South Africa.
  • Hatherill M; South African Tuberculosis Vaccine Initiative, Institute of Infectious Disease and Molecular Medicine, Department of Paediatrics and Child Health, University of Cape Town, Cape Town 7935, South Africa.
  • Hussey G; South African Tuberculosis Vaccine Initiative, Institute of Infectious Disease and Molecular Medicine, Department of Paediatrics and Child Health, University of Cape Town, Cape Town 7935, South Africa.
  • Mahomed H; South African Tuberculosis Vaccine Initiative, Institute of Infectious Disease and Molecular Medicine, Department of Paediatrics and Child Health, University of Cape Town, Cape Town 7935, South Africa.
  • Tameris M; South African Tuberculosis Vaccine Initiative, Institute of Infectious Disease and Molecular Medicine, Department of Paediatrics and Child Health, University of Cape Town, Cape Town 7935, South Africa.
  • McClain JB; South African Tuberculosis Vaccine Initiative, Institute of Infectious Disease and Molecular Medicine, Department of Paediatrics and Child Health, University of Cape Town, Cape Town 7935, South Africa.
  • Evans TG; South African Tuberculosis Vaccine Initiative, Institute of Infectious Disease and Molecular Medicine, Department of Paediatrics and Child Health, University of Cape Town, Cape Town 7935, South Africa.
  • Hanekom WA; Aeras, Rockville, Maryland 20850, USA.
  • Scriba TJ; Aeras, Rockville, Maryland 20850, USA.
  • McShane H; South African Tuberculosis Vaccine Initiative, Institute of Infectious Disease and Molecular Medicine, Department of Paediatrics and Child Health, University of Cape Town, Cape Town 7935, South Africa.
Nat Commun ; 7: 11290, 2016 04 12.
Article in En | MEDLINE | ID: mdl-27068708
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: BCG Vaccine / Lymphocyte Activation / CD4-Positive T-Lymphocytes / Vaccination Type of study: Clinical_trials / Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Adolescent / Humans / Infant Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2016 Type: Article Affiliation country: United kingdom
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: BCG Vaccine / Lymphocyte Activation / CD4-Positive T-Lymphocytes / Vaccination Type of study: Clinical_trials / Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Adolescent / Humans / Infant Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2016 Type: Article Affiliation country: United kingdom