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First-in-human phase I study of the DNA-repair inhibitor DT01 in combination with radiotherapy in patients with skin metastases from melanoma.
Le Tourneau, C; Dreno, B; Kirova, Y; Grob, J J; Jouary, T; Dutriaux, C; Thomas, L; Lebbé, C; Mortier, L; Saiag, P; Avril, M F; Maubec, E; Joly, P; Bey, P; Cosset, J M; Sun, J S; Asselain, B; Devun, F; Marty, M E; Dutreix, M.
Affiliation
  • Le Tourneau C; Department of Medical Oncology, Institut Curie, Paris & Saint-Cloud 75005, France.
  • Dreno B; EA7285, Versailles-Saint-Quentin-en-Yvelines University, Versailles 78000, France.
  • Kirova Y; CHU de Nantes-Hôtel Dieu, Nantes 44093, France.
  • Grob JJ; Radiotherapy Department, Institut Curie, Paris 75005, France.
  • Jouary T; La Timone Hospital-APHM, Aix-Marseille University, Marseille 13385, France.
  • Dutriaux C; Dermatology department, Saint-André Hospital, CHU de Bordeaux, Bordeaux 33000, France.
  • Thomas L; Dermatology department, Saint-André Hospital, CHU de Bordeaux, Bordeaux 33000, France.
  • Lebbé C; Lyon Sud Hospital Center, Lyon 1 University, Pierre Benite 69495, France.
  • Mortier L; Saint-Louis Hospital, APHP, Paris 75010, France.
  • Saiag P; Dermatology department, CHRU of Lille, Lille 59037, France.
  • Avril MF; Ambroise Paré Hospital, Boulogne Billancourt 92104, France.
  • Maubec E; Cochin hospital, APHP, Paris 75014, France.
  • Joly P; Bichat Hospital, Paris 75877, France.
  • Bey P; CHU Rouen, Charles-Nicolle, Rouen 76000, France.
  • Cosset JM; Institut Curie, Paris 75005, France.
  • Sun JS; Radiotherapy Department, Institut Curie, Paris 75005, France.
  • Asselain B; DNA Therapeutics, Evry 91058, France.
  • Devun F; Department of Biostatistics, Institut Curie, Paris 75005, France.
  • Marty ME; DNA Therapeutics, Evry 91058, France.
  • Dutreix M; Institut Curie, Orsay 91405, France.
Br J Cancer ; 114(11): 1199-205, 2016 May 24.
Article in En | MEDLINE | ID: mdl-27140316
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Radiation-Sensitizing Agents / Skin Neoplasms / DNA / Cholesterol / DNA Repair / Melanoma / Antineoplastic Agents Limits: Aged80 Language: En Journal: Br J Cancer Year: 2016 Type: Article Affiliation country: France
Fulltext
Print
XML
PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Radiation-Sensitizing Agents / Skin Neoplasms / DNA / Cholesterol / DNA Repair / Melanoma / Antineoplastic Agents Limits: Aged80 Language: En Journal: Br J Cancer Year: 2016 Type: Article Affiliation country: France