Assessment of hepatoprotective and nephroprotective potential of withaferin A on bromobenzene-induced injury in Swiss albino mice: possible involvement of mitochondrial dysfunction and inflammation.

Vedi, Mahima; Sabina, Evan Prince

Vedi, Mahima; Sabina, Evan Prince.

Affiliation

Vedi M; SBST, VIT University, Vellore, Tamil Nadu, 632014, India.
Sabina EP; SBST, VIT University, Vellore, Tamil Nadu, 632014, India. eps674@gmail.com.

Cell Biol Toxicol ; 32(5): 373-90, 2016 10.

Article in En | MEDLINE | ID: mdl-27250656

Subject(s)

Bromobenzenes/toxicity; Kidney/drug effects; Liver/drug effects; Mitochondria/drug effects; Withanolides/pharmacology; Animals; Antioxidants/pharmacology; Chemical and Drug Induced Liver Injury/etiology; Chemical and Drug Induced Liver Injury/prevention & control; Female; Inflammation/chemically induced; Inflammation/prevention & control; Interleukin-1beta/metabolism; Kidney Diseases/chemically induced; Kidney Diseases/prevention & control; Lipid Peroxidation/drug effects; Male; Mice; Mitochondria/physiology; Oxidants/pharmacology; Oxidative Stress/drug effects; Random Allocation; Tumor Necrosis Factor-alpha/metabolism

Key words

Anti-oxidant; Glutathione; Liver; Mitochondria

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Bromobenzenes / Withanolides / Kidney / Liver / Mitochondria Type of study: Etiology_studies Limits: Animals Language: En Journal: Cell Biol Toxicol Journal subject: TOXICOLOGIA Year: 2016 Type: Article Affiliation country: India

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