The methyltransferase Setdb1 is essential for meiosis and mitosis in mouse oocytes and early embryos.

Eymery, Angeline; Liu, Zichuan; Ozonov, Evgeniy A; Stadler, Michael B; Peters, Antoine H F M

Eymery, Angeline; Liu, Zichuan; Ozonov, Evgeniy A; Stadler, Michael B; Peters, Antoine H F M.

Affiliation

Eymery A; Friedrich Miescher Institute for Biomedical Research, Basel 4058, Switzerland.
Liu Z; Friedrich Miescher Institute for Biomedical Research, Basel 4058, Switzerland.
Ozonov EA; Friedrich Miescher Institute for Biomedical Research, Basel 4058, Switzerland.
Stadler MB; Friedrich Miescher Institute for Biomedical Research, Basel 4058, Switzerland Swiss Institute of Bioinformatics, Basel 4058, Switzerland.
Peters AH; Friedrich Miescher Institute for Biomedical Research, Basel 4058, Switzerland Faculty of Sciences, University of Basel, Basel 4056, Switzerland antoine.peters@fmi.ch.

Development ; 143(15): 2767-79, 2016 08 01.

Article in En | MEDLINE | ID: mdl-27317807

Subject(s)

Histone-Lysine N-Methyltransferase/metabolism; Meiosis/physiology; Mitosis/physiology; Oocytes/metabolism; Animals; Chromosome Segregation/genetics; Chromosome Segregation/physiology; Embryonic Development/genetics; Embryonic Development/physiology; Female; Histone-Lysine N-Methyltransferase/genetics; Kinetochores/metabolism; Male; Meiosis/genetics; Mice; Mitosis/genetics; Oocytes/cytology; Oogenesis/genetics; Oogenesis/physiology; Retroelements/genetics; Retroelements/physiology

Key words

Histone methylation; Meiosis; Mitosis; Pre-implantation development; Transcriptional regulation

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Oocytes / Histone-Lysine N-Methyltransferase / Meiosis / Mitosis Type of study: Prognostic_studies Limits: Animals Language: En Journal: Development Journal subject: BIOLOGIA / EMBRIOLOGIA Year: 2016 Type: Article Affiliation country: Switzerland

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