Process of Fragment-Based Lead Discovery-A Perspective from NMR.

Ma, Rongsheng; Wang, Pengchao; Wu, Jihui; Ruan, Ke

Ma, Rongsheng; Wang, Pengchao; Wu, Jihui; Ruan, Ke.

Affiliation

Ma R; Hefei National Laboratory for Physical Science at the Microscale, School of Life Sciences, University of Science and Technology of China, Hefei 230027, Anhui, China. mrs1988@mail.ustc.edu.cn.
Wang P; Hefei National Laboratory for Physical Science at the Microscale, School of Life Sciences, University of Science and Technology of China, Hefei 230027, Anhui, China. wpc1009@mail.ustc.edu.cn.
Wu J; Hefei National Laboratory for Physical Science at the Microscale, School of Life Sciences, University of Science and Technology of China, Hefei 230027, Anhui, China. wujihui@ustc.edu.cn.
Ruan K; Hefei National Laboratory for Physical Science at the Microscale, School of Life Sciences, University of Science and Technology of China, Hefei 230027, Anhui, China. kruan@ustc.edu.cn.

Molecules ; 21(7)2016 Jul 16.

Article in En | MEDLINE | ID: mdl-27438813

Subject(s)

Drug Discovery; Magnetic Resonance Spectroscopy; Computer Simulation; Drug Discovery/methods; Ligands; Magnetic Resonance Spectroscopy/methods; Models, Molecular; Molecular Conformation; Protein Binding; Small Molecule Libraries; Structure-Activity Relationship

Key words

NMR spectroscopy; fragment based lead discovery; proteinprotein interaction

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Magnetic Resonance Spectroscopy / Drug Discovery Language: En Journal: Molecules Journal subject: BIOLOGIA Year: 2016 Type: Article Affiliation country: China

Fulltext

XML

PubMed Links

Search on Google