Cytotoxic Oleanane-Type Saponins from the Leaves of Albizia anthelmintica Brongn.

Al-Sayed, Eman; Eldahshan, Omayma A; Bahgat, Dina M; Singab, Abdel Nasser B

Al-Sayed, Eman; Eldahshan, Omayma A; Bahgat, Dina M; Singab, Abdel Nasser B.

Affiliation

Al-Sayed E; Department of Pharmacognosy, Faculty of Pharmacy, Ain-Shams University, Cairo, 11566, Egypt.
Eldahshan OA; Department of Pharmacognosy, Faculty of Pharmacy, Ain-Shams University, Cairo, 11566, Egypt.
Bahgat DM; Department of Pharmacognosy, Faculty of Pharmacy, Ain-Shams University, Cairo, 11566, Egypt.
Singab AN; Department of Pharmacognosy, Faculty of Pharmacy, Ain-Shams University, Cairo, 11566, Egypt.

Chem Biodivers ; 13(12): 1666-1673, 2016 Dec.

Article in En | MEDLINE | ID: mdl-27450919

Subject(s)

Albizzia/chemistry; Antineoplastic Agents, Phytogenic/pharmacology; Oleanolic Acid/analogs & derivatives; Plant Leaves/chemistry; Saponins/pharmacology; Antineoplastic Agents, Phytogenic/chemistry; Antineoplastic Agents, Phytogenic/isolation & purification; Cell Proliferation/drug effects; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; HCT116 Cells; Hep G2 Cells; Humans; Inhibitory Concentration 50; Molecular Conformation; Oleanolic Acid/chemistry; Oleanolic Acid/isolation & purification; Oleanolic Acid/pharmacology; Saponins/chemistry; Saponins/isolation & purification; Structure-Activity Relationship

Key words

Albizia anthelmintica; Cytotoxicity; Fabaceae; MTT assay; Oleanane saponins

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Oleanolic Acid / Saponins / Plant Leaves / Albizzia / Antineoplastic Agents, Phytogenic Limits: Humans Language: En Journal: Chem Biodivers Journal subject: BIOQUIMICA / QUIMICA Year: 2016 Type: Article Affiliation country: Egypt

Fulltext

XML

PubMed Links

Search on Google