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Crowdsourced assessment of common genetic contribution to predicting anti-TNF treatment response in rheumatoid arthritis.
Sieberts, Solveig K; Zhu, Fan; García-García, Javier; Stahl, Eli; Pratap, Abhishek; Pandey, Gaurav; Pappas, Dimitrios; Aguilar, Daniel; Anton, Bernat; Bonet, Jaume; Eksi, Ridvan; Fornés, Oriol; Guney, Emre; Li, Hongdong; Marín, Manuel Alejandro; Panwar, Bharat; Planas-Iglesias, Joan; Poglayen, Daniel; Cui, Jing; Falcao, Andre O; Suver, Christine; Hoff, Bruce; Balagurusamy, Venkat S K; Dillenberger, Donna; Neto, Elias Chaibub; Norman, Thea; Aittokallio, Tero; Ammad-Ud-Din, Muhammad; Azencott, Chloe-Agathe; Bellón, Víctor; Boeva, Valentina; Bunte, Kerstin; Chheda, Himanshu; Cheng, Lu; Corander, Jukka; Dumontier, Michel; Goldenberg, Anna; Gopalacharyulu, Peddinti; Hajiloo, Mohsen; Hidru, Daniel; Jaiswal, Alok; Kaski, Samuel; Khalfaoui, Beyrem; Khan, Suleiman Ali; Kramer, Eric R; Marttinen, Pekka; Mezlini, Aziz M; Molparia, Bhuvan; Pirinen, Matti; Saarela, Janna.
Affiliation
  • Sieberts SK; Sage Bionetworks, Seattle, Washington 98115, USA.
  • Zhu F; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan 48109, USA.
  • García-García J; Structural Bioinformatics Group (GRIB/IMIM), Departament de Ciències Experimentals i de la Salut, Universitat Pompeu Fabra, Barcelona 08003, Spain.
  • Stahl E; Center for Statistical Genetics, Division of Psychiatric Genomics, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.
  • Pratap A; Icahn Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.
  • Pandey G; Sage Bionetworks, Seattle, Washington 98115, USA.
  • Pappas D; Icahn Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.
  • Aguilar D; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.
  • Anton B; Division of Rheumatology, Department of Medicine, Columbia University, New York, New York 10032, USA.
  • Bonet J; Corrona LLC, Southborough, Massachusetts 01772, USA.
  • Eksi R; Structural Bioinformatics Group (GRIB/IMIM), Departament de Ciències Experimentals i de la Salut, Universitat Pompeu Fabra, Barcelona 08003, Spain.
  • Fornés O; Structural Bioinformatics Group (GRIB/IMIM), Departament de Ciències Experimentals i de la Salut, Universitat Pompeu Fabra, Barcelona 08003, Spain.
  • Guney E; Structural Bioinformatics Group (GRIB/IMIM), Departament de Ciències Experimentals i de la Salut, Universitat Pompeu Fabra, Barcelona 08003, Spain.
  • Li H; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan 48109, USA.
  • Marín MA; Structural Bioinformatics Group (GRIB/IMIM), Departament de Ciències Experimentals i de la Salut, Universitat Pompeu Fabra, Barcelona 08003, Spain.
  • Panwar B; Center for Complex Network Research, Northeastern University, Boston, Massachusetts 02115, USA.
  • Planas-Iglesias J; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan 48109, USA.
  • Poglayen D; Structural Bioinformatics Group (GRIB/IMIM), Departament de Ciències Experimentals i de la Salut, Universitat Pompeu Fabra, Barcelona 08003, Spain.
  • Cui J; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan 48109, USA.
  • Falcao AO; Structural Bioinformatics Group (GRIB/IMIM), Departament de Ciències Experimentals i de la Salut, Universitat Pompeu Fabra, Barcelona 08003, Spain.
  • Suver C; Structural Bioinformatics Group (GRIB/IMIM), Departament de Ciències Experimentals i de la Salut, Universitat Pompeu Fabra, Barcelona 08003, Spain.
  • Hoff B; Division of Rheumatology, Immunology, and Allergy, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA.
  • Balagurusamy VSK; Department of Informatics, Faculty of Sciences, University of Lisbon, Lisbon 1749-016, Portugal.
  • Dillenberger D; Sage Bionetworks, Seattle, Washington 98115, USA.
  • Neto EC; Sage Bionetworks, Seattle, Washington 98115, USA.
  • Norman T; IBM T.J. Watson Research Center, Yorktown Heights, New York, New York 10598, USA.
  • Aittokallio T; IBM T.J. Watson Research Center, Yorktown Heights, New York, New York 10598, USA.
  • Ammad-Ud-Din M; Sage Bionetworks, Seattle, Washington 98115, USA.
  • Azencott CA; Sage Bionetworks, Seattle, Washington 98115, USA.
  • Bellón V; IBM T.J. Watson Research Center, Yorktown Heights, New York, New York 10598, USA.
  • Boeva V; Department of Computer Science, Aalto University, Espoo 02150, Finland.
  • Bunte K; Helsinki Institute for Information Technology (HIIT), Esbo 02150, Finland.
  • Chheda H; MINES ParisTech, PSL-Research University, CBIO-Centre for Computational Biology, Fontainebleau 77300, France.
  • Cheng L; Institut Curie, Paris 75248, France.
  • Corander J; Bioinformatics, Biostatistics, Epidemiology and Computational Systems Biology of Cancer, INSERM U900, Paris 75248, France.
  • Dumontier M; MINES ParisTech, PSL-Research University, CBIO-Centre for Computational Biology, Fontainebleau 77300, France.
  • Goldenberg A; Institut Curie, Paris 75248, France.
  • Gopalacharyulu P; Bioinformatics, Biostatistics, Epidemiology and Computational Systems Biology of Cancer, INSERM U900, Paris 75248, France.
  • Hajiloo M; MINES ParisTech, PSL-Research University, CBIO-Centre for Computational Biology, Fontainebleau 77300, France.
  • Hidru D; Institut Curie, Paris 75248, France.
  • Jaiswal A; Bioinformatics, Biostatistics, Epidemiology and Computational Systems Biology of Cancer, INSERM U900, Paris 75248, France.
  • Kaski S; Department of Computer Science, Aalto University, Espoo 02150, Finland.
  • Khalfaoui B; Helsinki Institute for Information Technology (HIIT), Esbo 02150, Finland.
  • Khan SA; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki FI-00014, Finland.
  • Kramer ER; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki FI-00014, Finland.
  • Marttinen P; Department of Computer Science, Aalto University, Espoo 02150, Finland.
  • Mezlini AM; Helsinki Institute for Information Technology (HIIT), Esbo 02150, Finland.
  • Molparia B; Helsinki Institute for Information Technology (HIIT), Esbo 02150, Finland.
  • Pirinen M; Department of Mathematics and Statistics, University of Helsinki, Helsinki FI-00014, Finland.
  • Saarela J; Stanford Center for Biomedical Informatics, Stanford University, Stanford, California 94305, USA.
Nat Commun ; 7: 12460, 2016 08 23.
Article in En | MEDLINE | ID: mdl-27549343
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Arthritis, Rheumatoid / Tumor Necrosis Factor-alpha / Genetic Predisposition to Disease / Polymorphism, Single Nucleotide / Antibodies, Monoclonal, Humanized Type of study: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2016 Type: Article Affiliation country: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Arthritis, Rheumatoid / Tumor Necrosis Factor-alpha / Genetic Predisposition to Disease / Polymorphism, Single Nucleotide / Antibodies, Monoclonal, Humanized Type of study: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2016 Type: Article Affiliation country: United States