A chemogenomic approach to understand the antifungal action of Lichen-derived vulpinic acid.

Kwon, Y; Cha, J; Chiang, J; Tran, G; Giaever, G; Nislow, C; Hur, J-S; Kwak, Y-S

Kwon, Y; Cha, J; Chiang, J; Tran, G; Giaever, G; Nislow, C; Hur, J-S; Kwak, Y-S.

Affiliation

Kwon Y; Division of Applied Life Science, Gyeongsang National University, Jinju, Korea.
Cha J; Department of Plant Medicine and Institute of Agriculture & Life Science, Gyeongsang National University, Jinju, Korea.
Chiang J; Pharmaceutical Sciences, University of British Columbia, Vancouver, BC, Canada.
Tran G; Pharmaceutical Sciences, University of British Columbia, Vancouver, BC, Canada.
Giaever G; Pharmaceutical Sciences, University of British Columbia, Vancouver, BC, Canada.
Nislow C; Pharmaceutical Sciences, University of British Columbia, Vancouver, BC, Canada.
Hur JS; Korean Lichen Research Institute, Suncheon National University, Suncheon, Korea.
Kwak YS; Department of Plant Medicine and Institute of Agriculture & Life Science, Gyeongsang National University, Jinju, Korea.

J Appl Microbiol ; 121(6): 1580-1591, 2016 Dec.

Article in En | MEDLINE | ID: mdl-27660105

Subject(s)

Antifungal Agents/pharmacology; Furans/pharmacology; Lichens/chemistry; Phenylacetates/pharmacology; Cell Cycle/drug effects; Gene Expression/drug effects; Genomics; Glycogen/metabolism; Haploinsufficiency; Homozygote; Yeasts/drug effects; Yeasts/genetics; Yeasts/metabolism

Key words

HIP-HOP assay; antifungal; lichen compound; mode-of-action; vulpinic acid

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Phenylacetates / Furans / Lichens / Antifungal Agents Language: En Journal: J Appl Microbiol Journal subject: MICROBIOLOGIA Year: 2016 Type: Article

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