Investigating the Molecular Mechanisms Behind Uncharacterized Cysteine Losses from Prediction of Their Oxidation State.

Raimondi, Daniele; Orlando, Gabriele; Messens, Joris; Vranken, Wim F

Raimondi, Daniele; Orlando, Gabriele; Messens, Joris; Vranken, Wim F.

Affiliation

Raimondi D; Interuniversity Institute of Bioinformatics in Brussels, ULB-VUB, Brussels, Belgium.
Orlando G; Structural Biology Brussels, Vrije Universiteit Brussel, Brussels, Belgium.
Messens J; Structural Biology Research Center (SBRC), VIB, Brussels, Belgium.
Vranken WF; Machine Learning Group, ULB, Brussels, Belgium.

Hum Mutat ; 38(1): 86-94, 2017 01.

Article in En | MEDLINE | ID: mdl-27667481

Subject(s)

Cysteine/genetics; Models, Biological; Mutation; Oxidation-Reduction; Algorithms; Amino Acid Substitution; Codon; Computational Biology/methods; Databases, Genetic; Genetic Association Studies; Humans; Intracellular Space/metabolism; Polymorphism, Single Nucleotide; Protein Transport; Reproducibility of Results; Software; Web Browser

Key words

cysteine mutation; cysteine oxidation prediction; disulfide bond; machine learning; molecular phenotype; single-nucleotide variants

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Oxidation-Reduction / Cysteine / Models, Biological / Mutation Type of study: Prognostic_studies / Risk_factors_studies Limits: Humans Language: En Journal: Hum Mutat Journal subject: GENETICA MEDICA Year: 2017 Type: Article Affiliation country: Belgium

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