Epimedium koreanum Nakai and its main constituent icariin suppress lipid accumulation during adipocyte differentiation of 3T3-L1 preadipocytes.

Han, Yunk-Yung; Song, Mi-Young; Hwang, Min-Sub; Hwang, Ji-Hye; Park, Yong-Ki; Jung, Hyo-Won

Han, Yunk-Yung; Song, Mi-Young; Hwang, Min-Sub; Hwang, Ji-Hye; Park, Yong-Ki; Jung, Hyo-Won.

Affiliation

Han YY; Korean Medicine R&D Center, College of Korean Medicine, Dongguk University, Gyeongju 38066, Republic of Korea.
Song MY; Korean Medicine R&D Center, College of Korean Medicine, Dongguk University, Gyeongju 38066, Republic of Korea; Department of Rehabilitation Medicine of Korean Medicine, College of Korean Medicine, Dongguk University, Gyeongju 38066, Republic of Korea.
Hwang MS; Department of Acupuncture & Moxibustion, College of Korean Medicine, Dongguk University, Gyeongju 38066, Republic of Korea.
Hwang JH; Korean Medicine R&D Center, College of Korean Medicine, Dongguk University, Gyeongju 38066, Republic of Korea.
Park YK; Korean Medicine R&D Center, College of Korean Medicine, Dongguk University, Gyeongju 38066, Republic of Korea; Department of Herbology, College of Korean Medicine, Dongguk University, Gyeongju 38066, Republic of Korea.
Jung HW; Korean Medicine R&D Center, College of Korean Medicine, Dongguk University, Gyeongju 38066, Republic of Korea; Department of Herbology, College of Korean Medicine, Dongguk University, Gyeongju 38066, Republic of Korea. Electronic address: tenzing2@hanmail.net.

Chin J Nat Med ; 14(9): 671-676, 2016 Sep.

Article in En | MEDLINE | ID: mdl-27667512

Subject(s)

Adipocytes/drug effects; Adipogenesis/drug effects; Epimedium/chemistry; Flavonoids/pharmacology; Lipid Metabolism/drug effects; Plant Extracts/pharmacology; 3T3-L1 Cells; Adipocytes/cytology; Adipocytes/metabolism; Animals; CCAAT-Enhancer-Binding Protein-alpha/genetics; CCAAT-Enhancer-Binding Protein-alpha/metabolism; Mice; PPAR gamma/genetics; PPAR gamma/metabolism; Sterol Regulatory Element Binding Protein 1/genetics; Sterol Regulatory Element Binding Protein 1/metabolism

Key words

3T3-L1 cells; Epimedium koreanum Nakai; Herba Epimedii; Icariin; Obesity

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Flavonoids / Plant Extracts / Adipocytes / Epimedium / Adipogenesis / Lipid Metabolism Limits: Animals Language: En Journal: Chin J Nat Med Year: 2016 Type: Article

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