Conductive Hearing Loss Has Long-Lasting Structural and Molecular Effects on Presynaptic and Postsynaptic Structures of Auditory Nerve Synapses in the Cochlear Nucleus.

Clarkson, Cheryl; Antunes, Flora M; Rubio, Maria E

Clarkson, Cheryl; Antunes, Flora M; Rubio, Maria E.

Affiliation

Clarkson C; Departments of Otolaryngology and.
Antunes FM; Departments of Otolaryngology and.
Rubio ME; Departments of Otolaryngology and Neurobiology and Center for the Neural Basis of Cognition, University of Pittsburgh, Pittsburgh, Pennsylvania 15261 mer@pitt.edu.

J Neurosci ; 36(39): 10214-27, 2016 09 28.

Article in En | MEDLINE | ID: mdl-27683915

Subject(s)

Cochlear Nerve/pathology; Cochlear Nerve/physiopathology; Cochlear Nucleus/pathology; Cochlear Nucleus/physiopathology; Hearing Loss, Conductive/pathology; Hearing Loss, Conductive/physiopathology; Synapses/pathology; Animals; Auditory Perception; Long-Term Potentiation; Long-Term Synaptic Depression; Male; Presynaptic Terminals/metabolism; Presynaptic Terminals/pathology; Rats; Rats, Sprague-Dawley; Synapses/metabolism; Synaptic Potentials

Key words

3D reconstructions; AMPA receptors; postembedding immunogold labeling; postsynaptic density; synaptic vesicles; vGluT1

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Synapses / Cochlear Nerve / Cochlear Nucleus / Hearing Loss, Conductive Limits: Animals Language: En Journal: J Neurosci Year: 2016 Type: Article

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