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Genetic Adaptation and Neandertal Admixture Shaped the Immune System of Human Populations.
Quach, Hélène; Rotival, Maxime; Pothlichet, Julien; Loh, Yong-Hwee Eddie; Dannemann, Michael; Zidane, Nora; Laval, Guillaume; Patin, Etienne; Harmant, Christine; Lopez, Marie; Deschamps, Matthieu; Naffakh, Nadia; Duffy, Darragh; Coen, Anja; Leroux-Roels, Geert; Clément, Frederic; Boland, Anne; Deleuze, Jean-François; Kelso, Janet; Albert, Matthew L; Quintana-Murci, Lluis.
Affiliation
  • Quach H; Human Evolutionary Genetics Unit, Institut Pasteur, Paris 75015, France; CNRS, URA3012, Paris 75015, France; Center of Bioinformatics, Biostatistics and Integrative Biology, Institut Pasteur, Paris 75015, France.
  • Rotival M; Human Evolutionary Genetics Unit, Institut Pasteur, Paris 75015, France; CNRS, URA3012, Paris 75015, France; Center of Bioinformatics, Biostatistics and Integrative Biology, Institut Pasteur, Paris 75015, France.
  • Pothlichet J; Human Evolutionary Genetics Unit, Institut Pasteur, Paris 75015, France; CNRS, URA3012, Paris 75015, France; Center of Bioinformatics, Biostatistics and Integrative Biology, Institut Pasteur, Paris 75015, France.
  • Loh YE; Human Evolutionary Genetics Unit, Institut Pasteur, Paris 75015, France; CNRS, URA3012, Paris 75015, France; Center of Bioinformatics, Biostatistics and Integrative Biology, Institut Pasteur, Paris 75015, France.
  • Dannemann M; Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Leipzig 04103, Germany.
  • Zidane N; Human Evolutionary Genetics Unit, Institut Pasteur, Paris 75015, France; CNRS, URA3012, Paris 75015, France; Center of Bioinformatics, Biostatistics and Integrative Biology, Institut Pasteur, Paris 75015, France.
  • Laval G; Human Evolutionary Genetics Unit, Institut Pasteur, Paris 75015, France; CNRS, URA3012, Paris 75015, France; Center of Bioinformatics, Biostatistics and Integrative Biology, Institut Pasteur, Paris 75015, France.
  • Patin E; Human Evolutionary Genetics Unit, Institut Pasteur, Paris 75015, France; CNRS, URA3012, Paris 75015, France; Center of Bioinformatics, Biostatistics and Integrative Biology, Institut Pasteur, Paris 75015, France.
  • Harmant C; Human Evolutionary Genetics Unit, Institut Pasteur, Paris 75015, France; CNRS, URA3012, Paris 75015, France; Center of Bioinformatics, Biostatistics and Integrative Biology, Institut Pasteur, Paris 75015, France.
  • Lopez M; Human Evolutionary Genetics Unit, Institut Pasteur, Paris 75015, France; CNRS, URA3012, Paris 75015, France; Center of Bioinformatics, Biostatistics and Integrative Biology, Institut Pasteur, Paris 75015, France; Université Pierre et Marie Curie, Cellule Pasteur, Institut Pasteur, Paris 75015, Franc
  • Deschamps M; Human Evolutionary Genetics Unit, Institut Pasteur, Paris 75015, France; CNRS, URA3012, Paris 75015, France; Center of Bioinformatics, Biostatistics and Integrative Biology, Institut Pasteur, Paris 75015, France; Université Pierre et Marie Curie, Cellule Pasteur, Institut Pasteur, Paris 75015, Franc
  • Naffakh N; Molecular Genetics of RNA Viruses Unit, Institut Pasteur, Paris 75015, France.
  • Duffy D; Dendritic Cell Immunobiology Unit, Institut Pasteur, Paris 75015, France.
  • Coen A; Center for Vaccinology, Ghent University and University Hospital, Ghent 9000, Belgium.
  • Leroux-Roels G; Center for Vaccinology, Ghent University and University Hospital, Ghent 9000, Belgium.
  • Clément F; Center for Vaccinology, Ghent University and University Hospital, Ghent 9000, Belgium.
  • Boland A; Centre National de Génotypage, CEA, Evry 91000, France.
  • Deleuze JF; Centre National de Génotypage, CEA, Evry 91000, France.
  • Kelso J; Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Leipzig 04103, Germany.
  • Albert ML; Dendritic Cell Immunobiology Unit, Institut Pasteur, Paris 75015, France; Department of Cancer Immunology, Genentech, South San Francisco, CA 94080, USA.
  • Quintana-Murci L; Human Evolutionary Genetics Unit, Institut Pasteur, Paris 75015, France; CNRS, URA3012, Paris 75015, France; Center of Bioinformatics, Biostatistics and Integrative Biology, Institut Pasteur, Paris 75015, France. Electronic address: quintana@pasteur.fr.
Cell ; 167(3): 643-656.e17, 2016 Oct 20.
Article in En | MEDLINE | ID: mdl-27768888
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Adaptation, Physiological / Adaptive Immunity / Neanderthals Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Cell Year: 2016 Type: Article Affiliation country: France
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Adaptation, Physiological / Adaptive Immunity / Neanderthals Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Cell Year: 2016 Type: Article Affiliation country: France