Model averaging for treatment effect estimation in subgroups.

Bornkamp, Björn; Ohlssen, David; Magnusson, Baldur P; Schmidli, Heinz

Bornkamp, Björn; Ohlssen, David; Magnusson, Baldur P; Schmidli, Heinz.

Affiliation

Bornkamp B; Novartis Pharma AG, Basel, CH-4002, Switzerland.
Ohlssen D; Novartis Pharmaceuticals Corporation, East Hanover, New Jersey, 07936-1080, USA.
Magnusson BP; Novartis Pharma AG, Basel, CH-4002, Switzerland.
Schmidli H; Novartis Pharma AG, Basel, CH-4002, Switzerland.

Pharm Stat ; 16(2): 133-142, 2017 03.

Article in En | MEDLINE | ID: mdl-27935199

Subject(s)

Bayes Theorem; Clinical Trials as Topic/methods; Models, Statistical; Computer Simulation; Data Interpretation, Statistical; Humans; Research Design; Selection Bias; Uncertainty

Key words

Bayesian inference; exploratory study; proof of concept trial; shrinkage; subgroup analysis

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Clinical Trials as Topic / Models, Statistical / Bayes Theorem Type of study: Clinical_trials / Prognostic_studies / Risk_factors_studies Limits: Humans Language: En Journal: Pharm Stat Journal subject: FARMACOLOGIA Year: 2017 Type: Article Affiliation country: Switzerland

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