Stability and aggregation propensity do not fully account for the association of various germline variable domain gene segments with light chain amyloidosis.

Garay Sánchez, Sergio A; Rodríguez Álvarez, Francisco Javier; Zavala-Padilla, Guadalupe; Mejia-Cristobal, Luz María; Cruz-Rangel, Armando; Costas, Miguel; Fernández Velasco, D Alejandro; Melendez-Zajgla, Jorge; Del Pozo-Yauner, Luis

Garay Sánchez, Sergio A; Rodríguez Álvarez, Francisco Javier; Zavala-Padilla, Guadalupe; Mejia-Cristobal, Luz María; Cruz-Rangel, Armando; Costas, Miguel; Fernández Velasco, D Alejandro; Melendez-Zajgla, Jorge; Del Pozo-Yauner, Luis.

Biol Chem ; 398(4): 477-489, 2017 04 01.

Article in En | MEDLINE | ID: mdl-27935845

Subject(s)

Amyloid/genetics; Amyloidosis/genetics; Immunoglobulin Variable Region/genetics; Protein Aggregation, Pathological/genetics; Amino Acid Sequence; Germ-Line Mutation; Humans; Microscopy, Electron, Transmission; Protein Domains; Protein Stability; Sequence Alignment; Spectrometry, Fluorescence

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Immunoglobulin Variable Region / Protein Aggregation, Pathological / Amyloid / Amyloidosis Type of study: Risk_factors_studies Limits: Humans Language: En Journal: Biol Chem Journal subject: BIOQUIMICA Year: 2017 Type: Article

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