High-intensity focused ultrasonic ablation of sacral chordoma is feasible: a series of four cases and details of a national clinical trial.
Br J Neurosurg
; 31(4): 446-451, 2017 Aug.
Article
in En
| MEDLINE
| ID: mdl-27936948
ABSTRACT
High-intensity focused ultrasound describes the use of high-intensity focused ultrasound (HIFU) to ablate tumours without requiring an incision or other invasive procedure. This technique has been trialled on a range of tumours including uterine fibroids, prostate, liver and renal cancer. We describe our experience of using HIFU to ablate sacral chordoma in four patients with advanced tumours. Patients were treated under general anaesthetic or sedation using an ultrasound-guided HIFU device. HIFU therapy was associated with a reduction in tumour volume over time in three patients for whom follow up scans were available. Tumour necrosis was reliably demonstrated in two of the three patients. We have established a national trial to assess if HIFU may improve long-term outcome from sacral chordoma, details are given.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Sacrococcygeal Region
/
Spinal Neoplasms
/
Chordoma
/
High-Intensity Focused Ultrasound Ablation
Type of study:
Etiology_studies
Limits:
Adolescent
/
Child
/
Child, preschool
/
Female
/
Humans
/
Infant
/
Male
Language:
En
Journal:
Br J Neurosurg
Journal subject:
NEUROCIRURGIA
Year:
2017
Type:
Article
Affiliation country:
United kingdom