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Leukemic blasts program bone marrow adipocytes to generate a protumoral microenvironment.
Shafat, Manar S; Oellerich, Thomas; Mohr, Sebastian; Robinson, Stephen D; Edwards, Dylan R; Marlein, Christopher R; Piddock, Rachel E; Fenech, Matthew; Zaitseva, Lyubov; Abdul-Aziz, Amina; Turner, Jeremy; Watkins, Johnathan A; Lawes, Matthew; Bowles, Kristian M; Rushworth, Stuart A.
Affiliation
  • Shafat MS; Department of Molecular Haematology, Norwich Medical School, The University of East Anglia, Norwich Research Park, Norwich, United Kingdom.
  • Oellerich T; Department of Medicine II, Hematology/Oncology, Goethe University, Frankfurt, Germany.
  • Mohr S; German Cancer Research Center and German Cancer Consortium, Heidelberg, Germany.
  • Robinson SD; Department of Haematology, Cambridge Institute for Medical Research and Wellcome Trust/MRC Stem Cell Institute, University of Cambridge, Cambridge, United Kingdom.
  • Edwards DR; Department of Medicine II, Hematology/Oncology, Goethe University, Frankfurt, Germany.
  • Marlein CR; School of Biological Sciences, and.
  • Piddock RE; School of Biological Sciences, and.
  • Fenech M; Norwich Medical School, The University of East Anglia, Norwich Research Park, Norwich, United Kingdom.
  • Zaitseva L; Department of Molecular Haematology, Norwich Medical School, The University of East Anglia, Norwich Research Park, Norwich, United Kingdom.
  • Abdul-Aziz A; Department of Molecular Haematology, Norwich Medical School, The University of East Anglia, Norwich Research Park, Norwich, United Kingdom.
  • Turner J; Norwich Medical School, The University of East Anglia, Norwich Research Park, Norwich, United Kingdom.
  • Watkins JA; Elsie Bertram Diabetes Centre, Norfolk and Norwich University Hospitals NHS Trust, Norwich, United Kingdom.
  • Lawes M; Department of Molecular Haematology, Norwich Medical School, The University of East Anglia, Norwich Research Park, Norwich, United Kingdom.
  • Bowles KM; Department of Molecular Haematology, Norwich Medical School, The University of East Anglia, Norwich Research Park, Norwich, United Kingdom.
  • Rushworth SA; Norwich Medical School, The University of East Anglia, Norwich Research Park, Norwich, United Kingdom.
Blood ; 129(10): 1320-1332, 2017 03 09.
Article in En | MEDLINE | ID: mdl-28049638

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Bone Marrow Cells / Leukemia, Myeloid, Acute / Adipocytes / Tumor Microenvironment Limits: Adult / Aged / Aged80 / Animals / Female / Humans / Male / Middle aged Language: En Journal: Blood Year: 2017 Type: Article Affiliation country: United kingdom

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Bone Marrow Cells / Leukemia, Myeloid, Acute / Adipocytes / Tumor Microenvironment Limits: Adult / Aged / Aged80 / Animals / Female / Humans / Male / Middle aged Language: En Journal: Blood Year: 2017 Type: Article Affiliation country: United kingdom