Combining adverse pregnancy and perinatal outcomes for women exposed to antiepileptic drugs during pregnancy, using a latent trait model.

Wen, Xuerong; Hartzema, Abraham; Delaney, Joseph A; Brumback, Babette; Liu, Xuefeng; Egerman, Robert; Roth, Jeffrey; Segal, Rich; Meador, Kimford J

Wen, Xuerong; Hartzema, Abraham; Delaney, Joseph A; Brumback, Babette; Liu, Xuefeng; Egerman, Robert; Roth, Jeffrey; Segal, Rich; Meador, Kimford J.

Affiliation

Wen X; Health Outcomes, College of Pharmacy, University of Rhode Island, 7 Greenhouse Rd., Kingston, RI, 02881, USA. xuerongwen@uri.edu.
Hartzema A; Department of Pharmaceutical Outcome and Policy, University of Florida, Gainesville, FL, USA.
Delaney JA; Department of Epidemiology, University of Washington, Seattle, WA, USA.
Brumback B; Department of Biostatistics, University of Florida, Gainesville, FL, USA.
Liu X; Department of Biostatistics & Epidemiology, Systems, Population and Leadership, University of Michigan, Ann Arbor, MI, 48109, USA.
Egerman R; Department of Obstetrics & Gynecology, University of Florida, Gainesville, FL, USA.
Roth J; Department of Pediatrics, University of Florida, Gainesville, FL, USA.
Segal R; Department of Pharmaceutical Outcome and Policy, University of Florida, Gainesville, FL, USA.
Meador KJ; Department of Neurology & Neurological Sciences, Stanford University, Stanford, CA, USA.

BMC Pregnancy Childbirth ; 17(1): 10, 2017 01 06.

Article in En | MEDLINE | ID: mdl-28061833

Subject(s)

Anticonvulsants/adverse effects; Epilepsy/drug therapy; Pregnancy Complications/drug therapy; Prenatal Exposure Delayed Effects/chemically induced; Valproic Acid/adverse effects; Abnormalities, Drug-Induced/epidemiology; Abnormalities, Drug-Induced/etiology; Adult; Female; Florida; Humans; Infant, Low Birth Weight; Patient Outcome Assessment; Pregnancy; Pregnancy Outcome; Prenatal Exposure Delayed Effects/epidemiology; Retrospective Studies

Key words

Adverse perinatal outcome; Adverse pregnancy outcome; Antiepileptic drugs; Combining outcomes; Latent trait model; Valproate

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pregnancy Complications / Prenatal Exposure Delayed Effects / Valproic Acid / Epilepsy / Anticonvulsants Type of study: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Adult / Female / Humans / Pregnancy Country/Region as subject: America do norte Language: En Journal: BMC Pregnancy Childbirth Journal subject: OBSTETRICIA Year: 2017 Type: Article Affiliation country: United States

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