Novel oral glucose-lowering drugs are associated with lower risk of all-cause mortality, cardiovascular events and severe hypoglycaemia compared with insulin in patients with type 2 diabetes.

Nyström, Thomas; Bodegard, Johan; Nathanson, David; Thuresson, Marcus; Norhammar, Anna; Eriksson, Jan W

Nyström, Thomas; Bodegard, Johan; Nathanson, David; Thuresson, Marcus; Norhammar, Anna; Eriksson, Jan W.

Affiliation

Nyström T; Unit for Diabetes Research, Division of Internal Medicine, Department of Clinical Science and Education, Karolinska Institute, Södersjukhuset, Stockholm, Sweden.
Bodegard J; AstraZeneca Nordic-Baltic, Södertälje, Sweden.
Nathanson D; Unit for Diabetes Research, Division of Internal Medicine, Department of Clinical Science and Education, Karolinska Institute, Södersjukhuset, Stockholm, Sweden.
Thuresson M; Cardiology Unit, Department of Medicine, Solna, Karolinska Institute, Stockholm, Sweden.
Norhammar A; Capio S:t Görans Hospital, Stockholm, Sweden.
Eriksson JW; Statisticon AB, Uppsala, Sweden.

Diabetes Obes Metab ; 19(6): 831-841, 2017 06.

Article in En | MEDLINE | ID: mdl-28116795

Subject(s)

Benzhydryl Compounds/therapeutic use; Cardiovascular Diseases/etiology; Diabetes Mellitus, Type 2/mortality; Dipeptidyl-Peptidase IV Inhibitors/therapeutic use; Glucosides/therapeutic use; Hypoglycemia/etiology; Hypoglycemic Agents/therapeutic use; Administration, Oral; Aged; Cardiovascular Diseases/epidemiology; Cause of Death; Diabetes Mellitus, Type 2/complications; Diabetes Mellitus, Type 2/drug therapy; Female; Humans; Hypoglycemia/epidemiology; Male; Middle Aged; Propensity Score; Proportional Hazards Models; Registries; Risk Factors; Sweden

Key words

DPP-4 inhibitor; cardiovascular disease; dapagliflozin; hypoglycaemia; pharmaco-epidemiology; type 2 diabetes

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Benzhydryl Compounds / Cardiovascular Diseases / Diabetes Mellitus, Type 2 / Dipeptidyl-Peptidase IV Inhibitors / Glucosides / Hypoglycemia / Hypoglycemic Agents Type of study: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Aged / Female / Humans / Male / Middle aged Country/Region as subject: Europa Language: En Journal: Diabetes Obes Metab Journal subject: ENDOCRINOLOGIA / METABOLISMO Year: 2017 Type: Article Affiliation country: Sweden

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