Activity of chemokines in prostate and renal tumors and their potential role as future therapeutic targets.
Future Oncol
; 13(12): 1105-1114, 2017 May.
Article
in En
| MEDLINE
| ID: mdl-28147707
ABSTRACT
Chemokines are a class of low-molecular-weight proteins that induce chemotaxis and are implicated in the modulation of angiogenesis. The imbalance among angiogenic and antiangiogenic chemokines can promote the development of several conditions, including chronic inflammation, dysplastic transformation and cancer. In this review, we describe the activity and clinical significance of chemokines in prostate and renal tumors and provide an update on ongoing studies in this setting.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Prostatic Neoplasms
/
Chemokines
/
Kidney Neoplasms
Limits:
Animals
/
Female
/
Humans
/
Male
Language:
En
Journal:
Future Oncol
Year:
2017
Type:
Article
Affiliation country:
Italy