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Altered methylation of specific DNA loci in the liver of Bhmt-null mice results in repression of Iqgap2 and F2rl2 and is associated with development of preneoplastic foci.
Lupu, Daniel S; Orozco, Luz D; Wang, Ying; Cullen, John M; Pellegrini, Matteo; Zeisel, Steven H.
Affiliation
  • Lupu DS; Department of Nutrition, Nutrition Research Institute, University of North Carolina at Chapel Hill, Kannapolis, North Carolina, USA.
  • Orozco LD; Department of Molecular, Cell, and Developmental Biology, University of California, Los Angeles, Los Angeles, California, USA.
  • Wang Y; Department of Clinical Nutrition, School of Medicine, Xin Hua Hospital, Shanghai Jiao Tong University, Shanghai, China.
  • Cullen JM; North Carolina State University, College of Veterinary Medicine, Raleigh, North Carolina, USA.
  • Pellegrini M; Department of Molecular, Cell, and Developmental Biology, University of California, Los Angeles, Los Angeles, California, USA.
  • Zeisel SH; Department of Nutrition, Nutrition Research Institute, University of North Carolina at Chapel Hill, Kannapolis, North Carolina, USA; steven_zeisel@unc.edu.
FASEB J ; 31(5): 2090-2103, 2017 05.
Article in En | MEDLINE | ID: mdl-28179424
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Precancerous Conditions / DNA / Receptors, Thrombin / DNA Methylation / Ras GTPase-Activating Proteins / Folic Acid / Liver Type of study: Risk_factors_studies Limits: Animals Language: En Journal: FASEB J Journal subject: BIOLOGIA / FISIOLOGIA Year: 2017 Type: Article Affiliation country: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Precancerous Conditions / DNA / Receptors, Thrombin / DNA Methylation / Ras GTPase-Activating Proteins / Folic Acid / Liver Type of study: Risk_factors_studies Limits: Animals Language: En Journal: FASEB J Journal subject: BIOLOGIA / FISIOLOGIA Year: 2017 Type: Article Affiliation country: United States