Efficacy of safranal to cisplatin-induced nephrotoxicity.

Karafakioglu, Yasemin Sunucu; Bozkurt, Mehmet Fatih; Hazman, Ömer; Fidan, A Fatih

Karafakioglu, Yasemin Sunucu; Bozkurt, Mehmet Fatih; Hazman, Ömer; Fidan, A Fatih.

Affiliation

Karafakioglu YS; Department of Science Education, Faculty of Education, Usak University, Usak, Turkey yasemin.sunucu@usak.edu.tr.
Bozkurt MF; Department of Pathology, Faculty of Veterinary Medicine, University of Afyon Kocatepe, Afyonkarahisar, Turkey.
Hazman Ö; Department of Chemistry, Biochemistry Division, Faculty of Science and Arts, Afyon Kocatepe University, Afyonkarahisar, Turkey.
Fidan AF; Department of Biochemistry, Faculty of Veterinary Medicine, University of Afyon Kocatepe, Afyonkarahisar, Turkey.

Biochem J ; 474(7): 1195-1203, 2017 03 20.

Article in En | MEDLINE | ID: mdl-28188255

Subject(s)

Antineoplastic Agents/toxicity; Cisplatin/toxicity; Cyclohexenes/pharmacology; Nephritis/drug therapy; Protective Agents/pharmacology; Renal Insufficiency/prevention & control; Terpenes/pharmacology; Animals; Cisplatin/antagonists & inhibitors; Creatinine/blood; Drug Administration Schedule; Glutathione/metabolism; Injections, Intraperitoneal; Kidney/drug effects; Kidney/metabolism; Kidney/pathology; Male; Malondialdehyde/metabolism; Nephritis/chemically induced; Nephritis/metabolism; Nephritis/pathology; Rats; Rats, Sprague-Dawley; Renal Insufficiency/chemically induced; Renal Insufficiency/metabolism; Renal Insufficiency/pathology; Urea/blood

Key words

antioxidants; cisplatin; histopathology; oxidative stress; safranal

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Terpenes / Cisplatin / Protective Agents / Renal Insufficiency / Cyclohexenes / Nephritis / Antineoplastic Agents Limits: Animals Language: En Journal: Biochem J Year: 2017 Type: Article Affiliation country: Turkey

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