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STIM1 activates CRAC channels through rotation of the pore helix to open a hydrophobic gate.
Yamashita, Megumi; Yeung, Priscilla S-W; Ing, Christopher E; McNally, Beth A; Pomès, Régis; Prakriya, Murali.
Affiliation
  • Yamashita M; Department of Pharmacology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611, USA.
  • Yeung PS; Department of Pharmacology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611, USA.
  • Ing CE; Molecular Structure and Function, Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada M5G 0A4.
  • McNally BA; Department of Biochemistry, University of Toronto, 101 College Street, Toronto, Ontario, Canada M5G IL7.
  • Pomès R; Department of Pharmacology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611, USA.
  • Prakriya M; Molecular Structure and Function, Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada M5G 0A4.
Nat Commun ; 8: 14512, 2017 02 21.
Article in En | MEDLINE | ID: mdl-28220789
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ion Channel Gating / Calcium / Stromal Interaction Molecule 1 / ORAI1 Protein / Neoplasm Proteins Type of study: Prognostic_studies Limits: Humans Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2017 Type: Article Affiliation country: United States
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ion Channel Gating / Calcium / Stromal Interaction Molecule 1 / ORAI1 Protein / Neoplasm Proteins Type of study: Prognostic_studies Limits: Humans Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2017 Type: Article Affiliation country: United States