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A Novel DNA Vaccine Platform Enhances Neo-antigen-like T Cell Responses against WT1 to Break Tolerance and Induce Anti-tumor Immunity.
Walters, Jewell N; Ferraro, Bernadette; Duperret, Elizabeth K; Kraynyak, Kimberly A; Chu, Jaemi; Saint-Fleur, Ashley; Yan, Jian; Levitsky, Hy; Khan, Amir S; Sardesai, Niranjan Y; Weiner, David B.
Affiliation
  • Walters JN; Inovio Pharmaceuticals, Inc., 660 West Germantown Pike, Suite 110, Plymouth Meeting, PA 19462, USA.
  • Ferraro B; Inovio Pharmaceuticals, Inc., 660 West Germantown Pike, Suite 110, Plymouth Meeting, PA 19462, USA.
  • Duperret EK; The Wistar Institute, 3601 Spruce St., Philadelphia, PA 19104, USA.
  • Kraynyak KA; Inovio Pharmaceuticals, Inc., 660 West Germantown Pike, Suite 110, Plymouth Meeting, PA 19462, USA.
  • Chu J; The Wistar Institute, 3601 Spruce St., Philadelphia, PA 19104, USA.
  • Saint-Fleur A; The Johns Hopkins University, Baltimore, MD 21231, USA.
  • Yan J; Inovio Pharmaceuticals, Inc., 660 West Germantown Pike, Suite 110, Plymouth Meeting, PA 19462, USA.
  • Levitsky H; The Johns Hopkins University, Baltimore, MD 21231, USA.
  • Khan AS; Inovio Pharmaceuticals, Inc., 660 West Germantown Pike, Suite 110, Plymouth Meeting, PA 19462, USA.
  • Sardesai NY; Inovio Pharmaceuticals, Inc., 660 West Germantown Pike, Suite 110, Plymouth Meeting, PA 19462, USA.
  • Weiner DB; The Wistar Institute, 3601 Spruce St., Philadelphia, PA 19104, USA. Electronic address: dweiner@wistar.org.
Mol Ther ; 25(4): 976-988, 2017 04 05.
Article in En | MEDLINE | ID: mdl-28237837

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Lymphocyte Subsets / Vaccines, DNA / WT1 Proteins / Immune Tolerance / Antigens, Neoplasm / Neoplasms Limits: Animals / Female / Humans / Male Language: En Journal: Mol Ther Journal subject: BIOLOGIA MOLECULAR / TERAPEUTICA Year: 2017 Type: Article Affiliation country: United States

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Lymphocyte Subsets / Vaccines, DNA / WT1 Proteins / Immune Tolerance / Antigens, Neoplasm / Neoplasms Limits: Animals / Female / Humans / Male Language: En Journal: Mol Ther Journal subject: BIOLOGIA MOLECULAR / TERAPEUTICA Year: 2017 Type: Article Affiliation country: United States