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Hsp90 inhibition destabilizes Ezh2 protein in alloreactive T cells and reduces graft-versus-host disease in mice.
Huang, Qingrong; He, Shan; Tian, Yuanyuan; Gu, Yuting; Chen, Pan; Li, Changhong; Huang, Jiefang; Liu, Yongnian; Yu, Hongshuang; Jin, Min; Hu, Shaoyan; Tong, Qing; Ma, Anqi; Jin, Jian; Hexner, Elizabeth; Fung, Henry; Reshef, Ran; Zhang, Yi; Zhang, Yanyun.
Affiliation
  • Huang Q; Key Laboratory of Stem Cell Biology, Institute of Health Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences and Shanghai Jiao Tong University School of Medicine, Shanghai, China.
  • He S; Key Laboratory of Stem Cell Biology, Institute of Health Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences and Shanghai Jiao Tong University School of Medicine, Shanghai, China.
  • Tian Y; Fels Institute for Cancer Research and Molecular Biology, Temple University, Philadelphia, PA.
  • Gu Y; Shanghai Institute of Immunology, Institutes of Medical Sciences, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
  • Chen P; Shanghai Institute of Immunology, Institutes of Medical Sciences, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
  • Li C; Division of Endocrinology and Department of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, University of Pennsylvania, Philadelphia, PA.
  • Huang J; Division of Endocrinology and Department of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, University of Pennsylvania, Philadelphia, PA.
  • Liu Y; Key Laboratory of Stem Cell Biology, Institute of Health Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences and Shanghai Jiao Tong University School of Medicine, Shanghai, China.
  • Yu H; Fels Institute for Cancer Research and Molecular Biology, Temple University, Philadelphia, PA.
  • Jin M; Key Laboratory of Stem Cell Biology, Institute of Health Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences and Shanghai Jiao Tong University School of Medicine, Shanghai, China.
  • Hu S; Key Laboratory of Stem Cell Biology, Institute of Health Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences and Shanghai Jiao Tong University School of Medicine, Shanghai, China.
  • Tong Q; Department of Hematology, Children's Hospital, Institutes for Translational Medicine, Soochow University, Suzhou, China.
  • Ma A; Fels Institute for Cancer Research and Molecular Biology, Temple University, Philadelphia, PA.
  • Jin J; Department of Pharmacological Sciences and.
  • Hexner E; Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY.
  • Fung H; Department of Pharmacological Sciences and.
  • Reshef R; Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY.
  • Zhang Y; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.
  • Zhang Y; Department of Hematology/Oncology, Fox Chase Cancer Center, Temple Health, Philadelphia, PA.
Blood ; 129(20): 2737-2748, 2017 05 18.
Article in En | MEDLINE | ID: mdl-28246193
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: T-Lymphocytes / HSP90 Heat-Shock Proteins / Enhancer of Zeste Homolog 2 Protein / Graft vs Host Disease Type of study: Prognostic_studies Limits: Animals Language: En Journal: Blood Year: 2017 Type: Article Affiliation country: China
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: T-Lymphocytes / HSP90 Heat-Shock Proteins / Enhancer of Zeste Homolog 2 Protein / Graft vs Host Disease Type of study: Prognostic_studies Limits: Animals Language: En Journal: Blood Year: 2017 Type: Article Affiliation country: China