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Therapeutic targeting of polycomb and BET bromodomain proteins in diffuse intrinsic pontine gliomas.
Piunti, Andrea; Hashizume, Rintaro; Morgan, Marc A; Bartom, Elizabeth T; Horbinski, Craig M; Marshall, Stacy A; Rendleman, Emily J; Ma, Quanhong; Takahashi, Yoh-Hei; Woodfin, Ashley R; Misharin, Alexander V; Abshiru, Nebiyu A; Lulla, Rishi R; Saratsis, Amanda M; Kelleher, Neil L; James, C David; Shilatifard, Ali.
Affiliation
  • Piunti A; Department of Biochemistry and Molecular Genetics, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
  • Hashizume R; Department of Biochemistry and Molecular Genetics, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
  • Morgan MA; Department of Neurological Surgery, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
  • Bartom ET; Department of Biochemistry and Molecular Genetics, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
  • Horbinski CM; Department of Biochemistry and Molecular Genetics, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
  • Marshall SA; Department of Neurological Surgery, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
  • Rendleman EJ; Department of Biochemistry and Molecular Genetics, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
  • Ma Q; Department of Biochemistry and Molecular Genetics, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
  • Takahashi YH; Department of Biochemistry and Molecular Genetics, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
  • Woodfin AR; Department of Neurological Surgery, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
  • Misharin AV; Department of Biochemistry and Molecular Genetics, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
  • Abshiru NA; Department of Biochemistry and Molecular Genetics, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
  • Lulla RR; Department of Medicine, Division of Pulmonology, and Department of Pediatrics, Division of Hematology-Oncology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
  • Saratsis AM; Department of Chemistry, Northwestern University, Evanston, Illinois, USA.
  • Kelleher NL; Department of Hematology, Oncology, Neuro-Oncology &Stem Cell Transplantation, Ann &Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois, USA.
  • James CD; Department of Neurological Surgery, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
  • Shilatifard A; Department of Surgery, Division of Pediatric Neurosurgery, Ann &Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois, USA.
Nat Med ; 23(4): 493-500, 2017 Apr.
Article in En | MEDLINE | ID: mdl-28263307
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Chromatin / Histones / Nucleosomes / Gene Expression Regulation, Neoplastic / RNA-Binding Proteins / Brain Stem Neoplasms / Histone Code / Polycomb Repressive Complex 2 / Glioma Limits: Animals / Humans Language: En Journal: Nat Med Journal subject: BIOLOGIA MOLECULAR / MEDICINA Year: 2017 Type: Article Affiliation country: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Chromatin / Histones / Nucleosomes / Gene Expression Regulation, Neoplastic / RNA-Binding Proteins / Brain Stem Neoplasms / Histone Code / Polycomb Repressive Complex 2 / Glioma Limits: Animals / Humans Language: En Journal: Nat Med Journal subject: BIOLOGIA MOLECULAR / MEDICINA Year: 2017 Type: Article Affiliation country: United States