Heterarchy of transcription factors driving basal and luminal cell phenotypes in human urothelium.

Fishwick, Carl; Higgins, Janet; Percival-Alwyn, Lawrence; Hustler, Arianna; Pearson, Joanna; Bastkowski, Sarah; Moxon, Simon; Swarbreck, David; Greenman, Chris D; Southgate, Jennifer

Fishwick, Carl; Higgins, Janet; Percival-Alwyn, Lawrence; Hustler, Arianna; Pearson, Joanna; Bastkowski, Sarah; Moxon, Simon; Swarbreck, David; Greenman, Chris D; Southgate, Jennifer.

Affiliation

Fishwick C; Jack Birch Unit for Molecular Carcinogenesis, Department of Biology, University of York, York YO10 5DD, UK.
Higgins J; Earlham Institute, Norwich Research Park, Norwich NR4 7UZ, UK.
Percival-Alwyn L; Earlham Institute, Norwich Research Park, Norwich NR4 7UZ, UK.
Hustler A; Jack Birch Unit for Molecular Carcinogenesis, Department of Biology, University of York, York YO10 5DD, UK.
Pearson J; Jack Birch Unit for Molecular Carcinogenesis, Department of Biology, University of York, York YO10 5DD, UK.
Bastkowski S; Earlham Institute, Norwich Research Park, Norwich NR4 7UZ, UK.
Moxon S; Earlham Institute, Norwich Research Park, Norwich NR4 7UZ, UK.
Swarbreck D; Earlham Institute, Norwich Research Park, Norwich NR4 7UZ, UK.
Greenman CD; School of Computing Sciences, University of East Anglia, Norwich NR4 7TJ, UK.
Southgate J; Jack Birch Unit for Molecular Carcinogenesis, Department of Biology, University of York, York YO10 5DD, UK.

Cell Death Differ ; 24(5): 809-818, 2017 05.

Article in En | MEDLINE | ID: mdl-28282036

Subject(s)

Cell Differentiation/genetics; Epithelial Cells/cytology; Epithelial Cells/metabolism; GATA3 Transcription Factor/genetics; Hepatocyte Nuclear Factor 3-alpha/genetics; Transcription Factors/genetics; Tumor Suppressor Proteins/genetics; CCCTC-Binding Factor/genetics; CCCTC-Binding Factor/metabolism; Cell Line; Chromatin/chemistry; Chromatin/metabolism; DNA-Binding Proteins/genetics; DNA-Binding Proteins/metabolism; Formaldehyde/chemistry; GATA3 Transcription Factor/antagonists & inhibitors; GATA3 Transcription Factor/metabolism; Gene Expression Regulation; Hepatocyte Nuclear Factor 3-alpha/antagonists & inhibitors; Hepatocyte Nuclear Factor 3-alpha/metabolism; Humans; PPAR gamma/genetics; PPAR gamma/metabolism; Phenotype; RNA, Messenger/genetics; RNA, Messenger/metabolism; RNA, Small Interfering/genetics; RNA, Small Interfering/metabolism; Regulatory Elements, Transcriptional; Sequence Analysis, RNA; Signal Transduction; Transcription Factors/antagonists & inhibitors; Transcription Factors/metabolism; Tumor Suppressor Proteins/antagonists & inhibitors; Tumor Suppressor Proteins/metabolism; Urothelium/cytology; Urothelium/metabolism

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Transcription Factors / Cell Differentiation / Tumor Suppressor Proteins / Epithelial Cells / GATA3 Transcription Factor / Hepatocyte Nuclear Factor 3-alpha Type of study: Prognostic_studies Limits: Humans Language: En Journal: Cell Death Differ Year: 2017 Type: Article Affiliation country: United kingdom

Fulltext

XML

PubMed Links

Search on Google