Sialylation Is Dispensable for Early Murine Embryonic Development in Vitro.

Abeln, Markus; Borst, Kristina M; Cajic, Samanta; Thiesler, Hauke; Kats, Elina; Albers, Iris; Kuhn, Maike; Kaever, Volkhard; Rapp, Erdmann; Münster-Kühnel, Anja; Weinhold, Birgit

Abeln, Markus; Borst, Kristina M; Cajic, Samanta; Thiesler, Hauke; Kats, Elina; Albers, Iris; Kuhn, Maike; Kaever, Volkhard; Rapp, Erdmann; Münster-Kühnel, Anja; Weinhold, Birgit.

Affiliation

Abeln M; Institute of Clinical Biochemistry, Hannover Medical School, Carl-Neuberg-Strasse 1, 30625, Hannover, Germany.
Borst KM; Institute of Clinical Biochemistry, Hannover Medical School, Carl-Neuberg-Strasse 1, 30625, Hannover, Germany.
Cajic S; Max Planck Institute for Dynamics of Complex Technical Systems, Sandtorstrasse 1, 39106, Magdeburg, Germany.
Thiesler H; Institute of Clinical Biochemistry, Hannover Medical School, Carl-Neuberg-Strasse 1, 30625, Hannover, Germany.
Kats E; Institute of Clinical Biochemistry, Hannover Medical School, Carl-Neuberg-Strasse 1, 30625, Hannover, Germany.
Albers I; Institute of Clinical Biochemistry, Hannover Medical School, Carl-Neuberg-Strasse 1, 30625, Hannover, Germany.
Kuhn M; TWINCORE Centre for Experimental and Clinical Infection Research GmbH, A joint venture between Hannover Medical School, Feodor-Lynen-Strasse 7, 30625, Hannover, Germany.
Kaever V; Helmholtz Centre for Infection Research, Inhoffenstrasse 7, 38124, Braunschweig, Germany.
Rapp E; Research Core Unit Metabolomics, Hannover Medical School, Carl-Neuberg-Strasse 1, 30625, Hannover, Germany.
Münster-Kühnel A; Max Planck Institute for Dynamics of Complex Technical Systems, Sandtorstrasse 1, 39106, Magdeburg, Germany.
Weinhold B; glyXera GmbH, Leipziger Strasse 44, 39120, Magdeburg, Germany.

Chembiochem ; 18(13): 1305-1316, 2017 07 04.

Article in En | MEDLINE | ID: mdl-28374933

Subject(s)

Germ Layers/metabolism; Mouse Embryonic Stem Cells/metabolism; Myocytes, Cardiac/metabolism; N-Acylneuraminate Cytidylyltransferase/deficiency; Pluripotent Stem Cells/metabolism; Sialic Acids/metabolism; Amino Sugars/metabolism; Animals; Cell Differentiation; Cell Line; Embryo, Mammalian; Embryoid Bodies/cytology; Embryoid Bodies/metabolism; Founder Effect; Galactose/metabolism; Gene Expression; Germ Layers/cytology; Glycoconjugates/metabolism; HEK293 Cells; Humans; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mouse Embryonic Stem Cells/cytology; Myocytes, Cardiac/cytology; N-Acylneuraminate Cytidylyltransferase/genetics; Pluripotent Stem Cells/cytology; Transcriptome

Key words

CMP-sialic acid synthase; differentiation; glycosylation; metabolism; sialic acids

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sialic Acids / N-Acylneuraminate Cytidylyltransferase / Myocytes, Cardiac / Pluripotent Stem Cells / Mouse Embryonic Stem Cells / Germ Layers Limits: Animals / Humans Language: En Journal: Chembiochem Journal subject: BIOQUIMICA Year: 2017 Type: Article Affiliation country: Germany

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