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Human Effector Memory T Helper Cells Engage with Mouse Macrophages and Cause Graft-versus-Host-Like Pathology in Skin of Humanized Mice Used in a Nonclinical Immunization Study.
Sundarasetty, Balasai; Volk, Valery; Theobald, Sebastian J; Rittinghausen, Susanne; Schaudien, Dirk; Neuhaus, Vanessa; Figueiredo, Constanca; Schneider, Andreas; Gerasch, Laura; Mucci, Adele; Moritz, Thomas; von Kaisenberg, Constantin; Spineli, Loukia M; Sewald, Katherina; Braun, Armin; Weigt, Henning; Ganser, Arnold; Stripecke, Renata.
Affiliation
  • Sundarasetty B; Regenerative Biology to Reconstructive Therapies (REBIRTH), Laboratory of Regenerative Immune Therapies Applied, Hannover Medical School, Hannover, Germany; Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany.
  • Volk V; Regenerative Biology to Reconstructive Therapies (REBIRTH), Laboratory of Regenerative Immune Therapies Applied, Hannover Medical School, Hannover, Germany; Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany.
  • Theobald SJ; Regenerative Biology to Reconstructive Therapies (REBIRTH), Laboratory of Regenerative Immune Therapies Applied, Hannover Medical School, Hannover, Germany; Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany.
  • Rittinghausen S; Department of Pathology, Fraunhofer Institute for Toxicology and Experimental Medicine Hannover, Hannover, Germany.
  • Schaudien D; Department of Pathology, Fraunhofer Institute for Toxicology and Experimental Medicine Hannover, Hannover, Germany.
  • Neuhaus V; Department of Airway Immunology, Fraunhofer Institute for Toxicology and Experimental Medicine Hannover, Hannover, Germany.
  • Figueiredo C; Department of Transfusion Medicine, Hannover Medical School, Hannover, Germany.
  • Schneider A; Regenerative Biology to Reconstructive Therapies (REBIRTH), Laboratory of Regenerative Immune Therapies Applied, Hannover Medical School, Hannover, Germany; Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany.
  • Gerasch L; Regenerative Biology to Reconstructive Therapies (REBIRTH), Laboratory of Regenerative Immune Therapies Applied, Hannover Medical School, Hannover, Germany; Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany.
  • Mucci A; Institute of Experimental Hematology, Hannover Medical School, Hannover, Germany.
  • Moritz T; Institute of Experimental Hematology, Hannover Medical School, Hannover, Germany.
  • von Kaisenberg C; Clinic of Gynecology and Obstetrics, Hannover Medical School, Hannover, Germany.
  • Spineli LM; Institute of Biostatistics, Hannover Medical School, Hannover, Germany.
  • Sewald K; Department of Airway Immunology, Fraunhofer Institute for Toxicology and Experimental Medicine Hannover, Hannover, Germany.
  • Braun A; Department of Airway Immunology, Fraunhofer Institute for Toxicology and Experimental Medicine Hannover, Hannover, Germany.
  • Weigt H; Department of Airway Immunology, Fraunhofer Institute for Toxicology and Experimental Medicine Hannover, Hannover, Germany.
  • Ganser A; Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany.
  • Stripecke R; Regenerative Biology to Reconstructive Therapies (REBIRTH), Laboratory of Regenerative Immune Therapies Applied, Hannover Medical School, Hannover, Germany; Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany. Electronic address: s
Am J Pathol ; 187(6): 1380-1398, 2017 Jun.
Article in En | MEDLINE | ID: mdl-28432872

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Skin / T-Lymphocytes, Helper-Inducer / Graft vs Host Disease / Macrophages Limits: Animals Language: En Journal: Am J Pathol Year: 2017 Type: Article Affiliation country: Germany

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Skin / T-Lymphocytes, Helper-Inducer / Graft vs Host Disease / Macrophages Limits: Animals Language: En Journal: Am J Pathol Year: 2017 Type: Article Affiliation country: Germany