Pharmacokinetics after a single dose of naloxone administered as a nasal spray in healthy volunteers.

Vanky, E; Hellmundt, L; Bondesson, U; Eksborg, S; Lundeberg, S

Vanky, E; Hellmundt, L; Bondesson, U; Eksborg, S; Lundeberg, S.

Affiliation

Vanky E; Department of Anesthesia and Intensive Care, Visby Hospital, Visby, Sweden.
Hellmundt L; Department of Pediatric Anesthesia and Intensive Care, Astrid Lindgren Children's Hospital, Karolinska University Hospital, Stockholm, Sweden.
Bondesson U; Department of Chemistry, Environment and Feed Hygiene, National Veterinary Institute (SVA), Uppsala, Sweden.
Eksborg S; Childhood Cancer Research Unit, Department of Woman and Child Health, Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden.
Lundeberg S; Department of Anesthesia and Intensive Care, Visby Hospital, Visby, Sweden.

Acta Anaesthesiol Scand ; 61(6): 636-640, 2017 Jul.

Article in En | MEDLINE | ID: mdl-28444856

Subject(s)

Naloxone/administration & dosage; Naloxone/pharmacokinetics; Narcotic Antagonists/administration & dosage; Narcotic Antagonists/pharmacokinetics; Administration, Intranasal; Adult; Area Under Curve; Chromatography, High Pressure Liquid; Cross-Over Studies; Female; Half-Life; Healthy Volunteers; Humans; Hypnotics and Sedatives/antagonists & inhibitors; Male; Middle Aged; Naloxone/adverse effects; Narcotic Antagonists/adverse effects; Nasal Sprays; Sufentanil/antagonists & inhibitors; Tandem Mass Spectrometry; Young Adult

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Naloxone / Narcotic Antagonists Type of study: Clinical_trials / Prognostic_studies Limits: Adult / Female / Humans / Male / Middle aged Language: En Journal: Acta Anaesthesiol Scand Year: 2017 Type: Article Affiliation country: Sweden

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