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GLI3 repressor determines Hedgehog pathway activation and is required for response to SMO antagonist glasdegib in AML.
Chaudhry, Parvesh; Singh, Mohan; Triche, Timothy J; Guzman, Monica; Merchant, Akil A.
Affiliation
  • Chaudhry P; Division of Hematology, Department of Medicine, USC Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA; and.
  • Singh M; Division of Hematology, Department of Medicine, USC Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA; and.
  • Triche TJ; Division of Hematology, Department of Medicine, USC Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA; and.
  • Guzman M; Division of Hematology and Medical Oncology, Department of Medicine, Weill Cornell Medical College, New York, NY.
  • Merchant AA; Division of Hematology, Department of Medicine, USC Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA; and.
Blood ; 129(26): 3465-3475, 2017 06 29.
Article in En | MEDLINE | ID: mdl-28487292
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Repressor Proteins / Leukemia, Myeloid, Acute / Kruppel-Like Transcription Factors / Hedgehog Proteins / Smoothened Receptor / Nerve Tissue Proteins Limits: Animals / Humans Language: En Journal: Blood Year: 2017 Type: Article
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Repressor Proteins / Leukemia, Myeloid, Acute / Kruppel-Like Transcription Factors / Hedgehog Proteins / Smoothened Receptor / Nerve Tissue Proteins Limits: Animals / Humans Language: En Journal: Blood Year: 2017 Type: Article