The influence of carbohydrate structure on the clearance of recombinant tissue-type plasminogen activator.

Hotchkiss, A; Refino, C J; Leonard, C K; O'Connor, J V; Crowley, C; McCabe, J; Tate, K; Nakamura, G; Powers, D; Levinson, A

Hotchkiss, A; Refino, C J; Leonard, C K; O'Connor, J V; Crowley, C; McCabe, J; Tate, K; Nakamura, G; Powers, D; Levinson, A.

Affiliation

Hotchkiss A; Department of Pharmacological Sciences, Genentech, Inc., South San Francisco, CA.

Thromb Haemost ; 60(2): 255-61, 1988 Oct 31.

Article in En | MEDLINE | ID: mdl-2851193

Subject(s)

Carbohydrates; Tissue Plasminogen Activator/pharmacokinetics; Animals; Cells, Cultured; Cricetinae; Glutamine/analysis; Mannose/analysis; Mutation; Oligosaccharides/analysis; Periodic Acid/pharmacology; Rabbits; Recombinant Proteins/pharmacokinetics

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Collection: 01-internacional Database: MEDLINE Main subject: Carbohydrates / Tissue Plasminogen Activator Limits: Animals Language: En Journal: Thromb Haemost Year: 1988 Type: Article Affiliation country: Canada

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