Cadmium stimulates metastasis-associated phenotype in triple-negative breast cancer cells through integrin and ß-catenin signaling.

Wei, Zhengxi; Shaikh, Zahir A

Wei, Zhengxi; Shaikh, Zahir A.

Affiliation

Wei Z; Center for Molecular Toxicology, Department of Biomedical and Pharmaceutical Sciences, College of Pharmacy, University of Rhode Island, Kingston, RI 02881, USA.
Shaikh ZA; Center for Molecular Toxicology, Department of Biomedical and Pharmaceutical Sciences, College of Pharmacy, University of Rhode Island, Kingston, RI 02881, USA. Electronic address: zshaikh@uri.edu.

Toxicol Appl Pharmacol ; 328: 70-80, 2017 08 01.

Article in En | MEDLINE | ID: mdl-28527916

Subject(s)

Cadmium/toxicity; Integrins/drug effects; Neoplasm Metastasis/pathology; Signal Transduction/drug effects; Triple Negative Breast Neoplasms/genetics; Triple Negative Breast Neoplasms/pathology; beta Catenin/drug effects; Cell Adhesion/drug effects; Cell Line, Tumor; Cell Movement/drug effects; Cell Proliferation/drug effects; Cytoskeleton/drug effects; Female; Gene Expression Regulation, Neoplastic/drug effects; Humans; MCF-7 Cells; Phenotype; Wound Healing/drug effects

Key words

Breast cancer; Cadmium; Cell migration; Integrin; ß-Catenin

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cadmium / Signal Transduction / Integrins / Beta Catenin / Triple Negative Breast Neoplasms / Neoplasm Metastasis Type of study: Risk_factors_studies Limits: Female / Humans Language: En Journal: Toxicol Appl Pharmacol Year: 2017 Type: Article Affiliation country: United States

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